Optical coherence tomography evaluation of macular edema after intravitreal triamcinolone acetonide in patients with parafoveal telangiectasis

Parafoveal telangiectasis (PT) is a developmental or acquired microvascular abnormality of the macula. Leakage of the abnormal parafoveal capillaries leads to macular edema with subsequent decrease in visual acuity. Intravitreal triamcinolone acetonide is recently widely used in the management of in...

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Bibliographic Details
Published in:European journal of ophthalmology 2006-09, Vol.16 (5), p.711-717
Main Authors: Cakir, M, Kapran, Z, Basar, D, Utine, C A, Eroglu, F, Perente, I
Format: Article
Language:English
Subjects:
Aged
Female
Fluorescein Angiography
Follow-Up Studies
Fovea Centralis - pathology
Fundus Oculi
Glucocorticoids - administration & dosage
Glucocorticoids - therapeutic use
Humans
Injections
Macular Edema - complications
Macular Edema - drug therapy
Macular Edema - pathology
Male
Middle Aged
Telangiectasis - complications
Telangiectasis - drug therapy
Telangiectasis - pathology
Tomography, Optical Coherence
Triamcinolone Acetonide - administration & dosage
Triamcinolone Acetonide - therapeutic use
Vitreous Body
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Summary:Parafoveal telangiectasis (PT) is a developmental or acquired microvascular abnormality of the macula. Leakage of the abnormal parafoveal capillaries leads to macular edema with subsequent decrease in visual acuity. Intravitreal triamcinolone acetonide is recently widely used in the management of intraocular proliferative, edematous, and neovascular diseases. This report presents the evaluation of three cases with PT in whom intravitreal triamcinolone acetonide (IVTA) injection was performed. Fundus fluorescein angiography (FA) and optical coherence tomography (OCT) were used in follow-up of the patients. Following pars plana intravitreal injection of 4 mg of triamcinolone acetonide, the patients had angiographic improvement of the macular edema and minimal decrease in retinal thickness on OCT, accompanied by improvement in visual acuity and subjective visual assessment. The results of the present study on parafoveal capillary telangiectasis suggest that the intravitreal injection of triamcinolone acetonide may be a therapeutic option to increase visual acuity and decrease vascular leakage on FA. Following IVTA procedure, follow-up of these patients with both OCT and FA is important for correct clinical evaluation. Future studies on this method seem to be warranted.
ISSN:1120-6721
1724-6016
DOI:10.1177/112067210601600508