Ambulatory 24‐h oesophageal impedance–pH recordings: reliability of automatic analysis for gastro‐oesophageal reflux assessment

Oesophageal pH–impedance monitoring allows detection of acid and non‐acid gastro‐oesophageal reflux (GOR) events. Visual analysis of impedance recording requires expertise. Our aim was to evaluate the efficacy of an automated analysis for GOR assessment. Seventy‐three patients with suspected GORD un...

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Bibliographic Details
Published in:Neurogastroenterology and motility 2006-11, Vol.18 (11), p.978-986
Main Authors: Roman, S., Bruley Des Varannes, S., Pouderoux, P., Chaput, U., Mion, F., Galmiche, J.‐p., Zerbib, F.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
automatic analysis
Automation
Esophageal pH Monitoring
Female
Gastroesophageal Reflux - diagnosis
gastro‐oesophageal reflux
human study
Humans
Male
Middle Aged
pH–impedance monitoring
Plethysmography, Impedance
proton pump inhibitors
Sensitivity and Specificity
Software
symptom index
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Summary:Oesophageal pH–impedance monitoring allows detection of acid and non‐acid gastro‐oesophageal reflux (GOR) events. Visual analysis of impedance recording requires expertise. Our aim was to evaluate the efficacy of an automated analysis for GOR assessment. Seventy‐three patients with suspected GORD underwent 24‐h oesophageal pH–impedance monitoring. Recordings analysis was performed visually (V) and automatically using Autoscan function (AS) of Bioview® software. A symptom index (SI) ≥50% was considered for a significant association between symptoms and reflux events. AS analysis detected more reflux events, especially non‐acid, liquid, pure gas and proximal events. Detection of oesophageal acid exposure and acid reflux events was similar with both analyses. Agreement between V and AS analysis was good (Kendall's coefficient W > 0.750, P 
ISSN:1350-1925
1365-2982
DOI:10.1111/j.1365-2982.2006.00825.x