Effect of Combination Therapy With Simvastatin and Carvedilol in Patients With Left Ventricular Dysfunction Complicated With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention

Background This study assessed the effects of combination therapy with simvastatin and carvedilol on clinical outcome in patients with left ventricular (LV) dysfunction after acute myocardial infarction (AMI). Methods and Results The study retrospectively analyzed the data from 672 patients with LV...

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Bibliographic Details
Published in:Circulation Journal 2006, Vol.70(10), pp.1269-1274
Main Authors: Hong, Young Joon, Jeong, Myung Ho, Hwang, Sun Ho, Yun, Nam Sik, Lee, Sang Rok, Hong, Seo Na, Kim, Kye Hun, Park, Hyung Wook, Kim, Ju Han, Ahn, Youngkeun, Cho, Jeong Gwan, Park, Jong Chun, Kang, Jung Chaee
Format: Article
Language:English
Subjects:
Adrenergic β-antagonists
Aged
Angioplasty, Balloon, Coronary
Carbazoles - administration & dosage
Carvedilol
Coronary artery disease
Death
Disease-Free Survival
Drug Evaluation
Drug Therapy, Combination
Female
Heart failure
Humans
Male
Middle Aged
Myocardial Infarction - drug therapy
Myocardial Infarction - mortality
Propanolamines - administration & dosage
Retrospective Studies
Simvastatin - administration & dosage
Statins
Stroke Volume - drug effects
Treatment Outcome
Ventricular Dysfunction, Left - complications
Ventricular Dysfunction, Left - drug therapy
Ventricular Dysfunction, Left - mortality
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Summary:Background This study assessed the effects of combination therapy with simvastatin and carvedilol on clinical outcome in patients with left ventricular (LV) dysfunction after acute myocardial infarction (AMI). Methods and Results The study retrospectively analyzed the data from 672 patients with LV dysfunction [LV ejection fraction (LVEF)
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.70.1269