Peptidomics for Cancer Diagnosis:  Present and Future

Analysis of peptides in biological fluids by mass spectrometry holds promise of providing diagnostic and prognostic information for cancer and other diseases. Before this technology is used clinically, it is important to understand its advantages and limitations. These are summarized, along with pro...

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Bibliographic Details
Published in:Journal of proteome research 2006-09, Vol.5 (9), p.2079-2082
Main Author: Diamandis, Eleftherios P
Format: Article
Language:English
Subjects:
Body Fluids - chemistry
Computational Biology - methods
Humans
Mass Spectrometry - methods
Neoplasms - diagnosis
Peptides - analysis
Peptides - isolation & purification
Proteomics - methods
Proteomics - trends
Sequence Analysis, Protein - methods
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Summary:Analysis of peptides in biological fluids by mass spectrometry holds promise of providing diagnostic and prognostic information for cancer and other diseases. Before this technology is used clinically, it is important to understand its advantages and limitations. These are summarized, along with proposals, on how to proceed in the future. Keywords: peptidomics • proteomics • cancer markers • mass spectrometry • diagnosis
ISSN:1535-3893
1535-3907
DOI:10.1021/pr060225u