Architecture and Evolution of Organic Chemistry

Organic syntheses reported in the literature between 1850 and 2000 are analyzed at the simplified level of a connected network (see the picture of the network for 1850). Fundamental statistical laws that govern organic syntheses are established. These laws allow the estimation of the synthetic and i...

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Bibliographic Details
Published in:Angewandte Chemie (International ed.) 2005-11, Vol.44 (44), p.7263-7269
Main Authors: Fialkowski, Marcin, Bishop, Kyle J. M., Chubukov, Victor A., Campbell, Christopher J., Grzybowski, Bartosz A.
Format: Article
Language:English
Subjects:
combinatorial chemistry
master equations
networks
organic reactions
stochastic modeling
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Summary:Organic syntheses reported in the literature between 1850 and 2000 are analyzed at the simplified level of a connected network (see the picture of the network for 1850). Fundamental statistical laws that govern organic syntheses are established. These laws allow the estimation of the synthetic and industrial usefulness of organic molecules.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200502272