Systematic review of laparoscopic versus open surgery for colorectal cancer

Background: This study compares the efficacy and safety of laparoscopic surgery (LS) and open surgery (OS) for colorectal cancer. Methods: An electronic search of the literature was undertaken to identify primary studies and systematic reviews. Information on the efficacy and safety of LS versus OS...

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Bibliographic Details
Published in:British journal of surgery 2006-08, Vol.93 (8), p.921-928
Main Authors: Reza, M. M., Blasco, J. A., Andradas, E., Cantero, R., Mayol, J.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Colectomy - adverse effects
Colectomy - methods
Colorectal Neoplasms - surgery
General aspects
Humans
Laparoscopy - adverse effects
Laparoscopy - methods
Length of Stay
Medical sciences
Postoperative Complications - etiology
Randomized Controlled Trials as Topic
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the digestive system
Treatment Outcome
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Summary:Background: This study compares the efficacy and safety of laparoscopic surgery (LS) and open surgery (OS) for colorectal cancer. Methods: An electronic search of the literature was undertaken to identify primary studies and systematic reviews. Information on the efficacy and safety of LS versus OS was analysed. A meta‐analysis was conducted to examine long‐term outcomes. Results: A systematic review published in 2000 and 12 more recent randomized clinical trials were identified. Compared with OS, LS reduced blood loss and pain, and resulted in a faster return of bowel function and earlier resumption of normal diet. Hospital stay was up to 2 days shorter after LS. No significant differences between the techniques were noted in the incidence of complications or postoperative mortality. The time required to complete LS was significantly longer (0·5–1·0 h more). No significant differences were found between the two procedures in terms of overall mortality, cancer‐related mortality or disease recurrence. Conclusion: LS takes longer than OS but offers several short‐term benefits. However, complication rates are similar for both procedures and no differences were found in long‐term outcomes. Copyright © 2006 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. Not much to choose between them
ISSN:0007-1323
1365-2168
DOI:10.1002/bjs.5430