Focal Fibrosis of the Breast Diagnosed by a Sonographically Guided Core Biopsy of Nonpalpable Lesions: Imaging Findings and Clinical Relevance

The purpose of this study was to evaluate the frequency of focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions, to characterize imaging features, and to evaluate their clinical relevance. In a retrospective review of 724 lesions that underwent sonogr...

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Bibliographic Details
Published in:Journal of ultrasound in medicine 2005-10, Vol.24 (10), p.1377-1384
Main Authors: You, Jai Kyung, Kim, Eun-Kyung, Kwak, Jin Young, Kim, Min Jung, Oh, Ki Keun, Park, Byeong-Woo, Yang, Woo Ik
Format: Article
Language:English
Subjects:
Adult
Aged
Biopsy, Needle - methods
Breast - abnormalities
Breast - pathology
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - epidemiology
Breast Neoplasms - pathology
Female
Fibrocystic Breast Disease - diagnostic imaging
Fibrocystic Breast Disease - epidemiology
Fibrocystic Breast Disease - pathology
Humans
Incidence
Mammography
Middle Aged
Retrospective Studies
Ultrasonography, Mammary - statistics & numerical data
Citations: Items that this one cites
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Summary:The purpose of this study was to evaluate the frequency of focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions, to characterize imaging features, and to evaluate their clinical relevance. In a retrospective review of 724 lesions that underwent sonographically guided core biopsy of nonpalpable breast lesions, 62 cases had a diagnosis of focal fibrosis. Two radiologists analyzed the sonographic and mammographic findings according to the Breast Imaging Reporting and Data System. The results were compared with histologic findings at surgery or imaging findings during surveillance. The incidence of focal fibrosis was 8.6% (62/724). Sonographic films were available in 56 cases, so 56 cases were reviewed for their sonographic findings. Among the mammograms reviewed, 64.7% (33/51) had negative findings. Among the sonograms reviewed, the most common features were oval shape (32/56, 57.1%), parallel orientation (36/56, 64.3%), microlobulated margin (24/56, 42.9%), abrupt interface (50/56, 89.3%), isoechoic pattern (42/56, 75.0%), and a lack of posterior acoustic features (45/56, 80.4%). The Breast Imaging Reporting and Data System final assessment was category 3 in 27 (48.2%) and category 4 in 29 (51.8%). Most of the category 4 lesions were category 4A (26/29, 89.7%). Surgical excision (n = 7) and follow-up for at least 1 year (n = 49) showed no malignancy. Focal fibrosis was found in 8.6% by a sonographically guided core biopsy of nonpalpable breast lesions. Most of the lesions were categorized as probably benign (category 3) or having a low suggestion of malignancy (category 4A). Focal fibrosis diagnosed at core biopsy can be managed with a 6-month follow-up protocol.
ISSN:0278-4297
1550-9613
DOI:10.7863/jum.2005.24.10.1377