A comparative study of a 595-nm with a 585-nm pulsed dye laser in refractory port wine stains

Summary Background  The pulsed dye laser (PDL) is the treatment of choice for port wine stains (PWS); however, some patients' PWS become refractory to further treatments. Technological advances have enabled new machines with the advent of surface cooling devices to deliver longer wavelengths an...

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Bibliographic Details
Published in:British journal of dermatology (1951) 2005-09, Vol.153 (3), p.601-606
Main Authors: Yung, A., Sheehan-Dare, R.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Dermatology
Female
Follow-Up Studies
Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue
Humans
Low-Level Light Therapy - methods
Male
Medical sciences
Middle Aged
port wine stain
Port-Wine Stain - radiotherapy
Prospective Studies
pulse dye laser
Radiotherapy Dosage
refractory
Treatment Outcome
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Summary:Summary Background  The pulsed dye laser (PDL) is the treatment of choice for port wine stains (PWS); however, some patients' PWS become refractory to further treatments. Technological advances have enabled new machines with the advent of surface cooling devices to deliver longer wavelengths and higher fluence more safely. These advances have the potential to achieve improved response rates in refractory PWS. There are few studies comparing the efficacy of standard PDL treatments for refractory PWS with the wider choice of treatment variables available from newer PDL machines. Objectives  To determine if there is any advantage of using a longer wavelength (595 nm) and pulse widths (1·5 ms, 6 ms and 20 ms) over conventional PDL settings (wavelength 585 nm, pulse width 1·5 ms) in refractory PWS. Methods  Eighteen consecutive consenting patients with Fitzpatrick skin types 1–4 with a mean age 35 years (range 17–59 years) with refractory PWS were treated routinely with three separate test areas using 595‐nm PDL (using three different pulse width settings of 1·5 ms, 6 ms and 20 ms), compared with test areas treated with 585‐nm PDL (pulse width 1·5 ms). All test areas were treated with an identical fluence (15 J cm−2), spot size (7 mm) and cooling setting (dynamic cooling 60 ms, delay 60 ms). Results  We found a statistically significant advantage of 595‐nm PDL (pulse width 1·5 ms) over 595‐nm PDL (pulse width 6 ms) (P 
ISSN:0007-0963
1365-2133
DOI:10.1111/j.1365-2133.2005.06707.x