Evaluation of the Ages and Stages Questionnaires in identifying children with neurosensory disability in the Magpie Trial follow-up study

Aim: To evaluate performance of the Ages and Stages Questionnaires (full ASQ), and a shortened version (short ASQ), in detecting children with severe neurosensory disability in the Magpie Trial follow‐up study. Methods: All children, born to women in the Magpie Trial and selected for follow‐up, with...

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Bibliographic Details
Published in:Acta Paediatrica 2007-12, Vol.96 (12), p.1803-1808
Main Authors: Yu, Ly-Mee, Hey, Edmund, Doyle, Lex W, Farrell, Barbara, Spark, Patsy, Altman, Doug G, Duley, Lelia
Format: Article
Language:English
Subjects:
Ages and stages questionnaires
Biological and medical sciences
Blindness - diagnosis
Cerebral Palsy - diagnosis
Child development
Child, Preschool
Clinical Trials as Topic
Deafness - diagnosis
Developmental Disabilities - diagnosis
Female
Follow-Up Studies
General aspects
Humans
Infant
Medical sciences
Neurosensory disability
Predictive Value of Tests
Sensitivity and Specificity
Surveys and Questionnaires
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Summary:Aim: To evaluate performance of the Ages and Stages Questionnaires (full ASQ), and a shortened version (short ASQ), in detecting children with severe neurosensory disability in the Magpie Trial follow‐up study. Methods: All children, born to women in the Magpie Trial and selected for follow‐up, with a completed full 30 items and/or short 9‐items ASQ were included in this analysis. Sensitivity and specificity, corrected for verification bias, were computed to assess detection ability. Results: Of the 2046 children who completed a full ASQ, 406 (19.8%) failed the assessment, 54 of whom had confirmed neurosensory disability. Adjusted sensitivity and specificity (95% confidence intervals) were 87.4% (62.9–96.6%), and 82.3% (80.5–83.9%), respectively. Two of the five domains in the full ASQ (Fine Motor and Problem Solving) contributed little to detection ability. Sensitivity and specificity for the short ASQ were 69.2% and 95.7%, respectively. Conclusions: Sensitivity of the full ASQ for severe neurosensory disability is generally good, and does not appear to be much reduced by restricting questions to three out of the five domains. The short ASQ reported here reduced performance, although this might be improved by a different choice of questions or scoring system.
ISSN:0803-5253
1651-2227
DOI:10.1111/j.1651-2227.2007.00517.x