Genetic data of 10 X-STRs in a Spanish population sample

Abstract In this work, we present population genetic data of 10 X-chromosome STRs (DXS8378, DXS9898, DXS8377, HPRTB, GATA172D05, DXS7423, DXS6809, DXS7132, DXS101 and DXS6789) obtained from sample of 145 unrelated female individuals belonging to Valencia (Spain), a region located in the east of the...

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Bibliographic Details
Published in:Forensic science international 2007-12, Vol.173 (2), p.193-196
Main Authors: Aler, M, Sánchez-Diz, P, Gomes, I, Gisbert, M, Carracedo, A, Amorim, A, Gusmão, L
Format: Article
Language:English
Subjects:
Animal populations
Biological and medical sciences
Chromosomes, Human, X
Daughters
DNA Fingerprinting
Female
Forensic medicine
Forensic sciences
Gene Frequency
General aspects
Genetic diversity
Genetics, Population
Humans
Iberian Peninsula
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Pathology
Polymerase Chain Reaction
Population data
Public health. Hygiene
Public health. Hygiene-occupational medicine
Spain
STRs
Tandem Repeat Sequences
X-chromosome
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Summary:Abstract In this work, we present population genetic data of 10 X-chromosome STRs (DXS8378, DXS9898, DXS8377, HPRTB, GATA172D05, DXS7423, DXS6809, DXS7132, DXS101 and DXS6789) obtained from sample of 145 unrelated female individuals belonging to Valencia (Spain), a region located in the east of the Iberian Peninsula. All the markers studied present high genetic diversities, similar to those previously reported in other European population samples. No deviations from Hardy–Weinberg equilibrium were observed, with the exception of DXS101 locus. Allele frequencies and parameters of forensic interest for each X-STR were calculated. High mean exclusion chance and power of discrimination values were obtained by combining these 10 X-linked markers. Population comparisons (exact test of population differentiation; pairwise genetic distances) were carried out and low genetic distances were found between our sample and those from other Spanish or European regions.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2006.10.023