A novel mouse model for assessment of male sexual function

Abstract A novel model to evaluate erectile, ejaculatory, and sexual behavior patterns in conscious mouse is presented. Corpus spongiosum of the penis (CSP) pressure was recorded by using telemetry and was correlated with erectile activity (penile elongations, cups, flips) during reflex induction an...

Full description

Saved in:
Bibliographic Details
Published in:Physiology & behavior 2007-08, Vol.91 (5), p.535-543
Main Authors: Soukhova-O'Hare, G.K, Schmidt, M.H, Nozdrachev, A.D, Gozal, D
Format: Article
Language:English
Subjects:
Animals
Appetitive Behavior - physiology
Corpus spongiosum pressure
Ejaculation
Ejaculation - physiology
Erection
Female
Male
Mice
Mice, Inbred C57BL
Models, Animal
Monitoring, Physiologic - veterinary
Mouse model
Penile Erection - physiology
Psychiatry
Sexual behavior
Sexual Behavior, Animal - physiology
Telemetry
Telemetry - veterinary
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract A novel model to evaluate erectile, ejaculatory, and sexual behavior patterns in conscious mouse is presented. Corpus spongiosum of the penis (CSP) pressure was recorded by using telemetry and was correlated with erectile activity (penile elongations, cups, flips) during reflex induction and spontaneous erections in freely moving mice. CSP pressure was also recorded during mating tests (mounts, intromissions with erections, ejaculations), as well as non-contact tests with estrous female mice. Erectile events were quantified in four sexual contexts (spontaneous erections, spinal reflexes, in mating and non-contact tests). The data demonstrate that CSP pressure monitoring is a valid technique for assessment of sexual function in freely moving mice.
ISSN:0031-9384
1873-507X
DOI:10.1016/j.physbeh.2007.04.016