The forces imposed by the novel T-shape Cu/LDPE nanocomposite intrauterine devices on the simulated uterine cavity

Abstract Background A simulated device was designed to study the forces, which are one of the most important factors relevant to the pain caused by the inserted intrauterine devices (IUDs), imposed by the novel T-shape copper/low-density polyethylene nanocomposite IUDs and the existing T-shape coppe...

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Bibliographic Details
Published in:Contraception (Stoneham) 2007-10, Vol.76 (4), p.326-330
Main Authors: Xia, Xianping, Xie, Changsheng, Wang, Yun, Cai, Shuizhou, Zhu, Changhong, Yang, Xiangliang
Format: Article
Language:English
Subjects:
Biological and medical sciences
Birth control
Copper
Cu/LDPE nanocomposite
Female
Forces
Genital system. Reproduction
Gynecology. Andrology. Obstetrics
Humans
Intrauterine Devices, Copper - adverse effects
IUDs
Materials Testing
Medical sciences
Models, Anatomic
Nanocomposites - chemistry
Nanocomposites - therapeutic use
Obstetrics and Gynecology
Other methods of contraception. Sterilization
Pain - etiology
Pharmacology. Drug treatments
Shapes
Stress, Mechanical
Uterus - physiology
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Summary:Abstract Background A simulated device was designed to study the forces, which are one of the most important factors relevant to the pain caused by the inserted intrauterine devices (IUDs), imposed by the novel T-shape copper/low-density polyethylene nanocomposite IUDs and the existing T-shape copper-containing IUDs (CuT 220C) on the uterine cavity. Study Design Tests were performed in a simulated uterine cavity with the same simulated uterine solution at a constant temperature of 37.0±0.1°C. Force and deformation were measured using the Digital Push Pull Force Gauge with a gauge of displacement. Results The novel T-shape nanocomposite IUD and the existing T-shape Cu-IUD (CuT 220C) have a similar relationship between force and deformation when they are removed from the simulated uterine cavity, but they have a quite different relationship when they are pressed by axial compressive loads. Conclusion It can be surmised that the novel T-shape nanocomposite IUD is superior to the existing T-shape Cu-IUD. It may alleviate the users' pain in future clinical application. Shape is a very important factor that affects the force imposed by the inserted IUDs, and it must be taken into account when a new IUD is designed.
ISSN:0010-7824
1879-0518
DOI:10.1016/j.contraception.2007.06.006