New Sensitive Fluorophores for Selective DNA Detection

4,7-Disubstituted benzothiadiazoles containing 1-arylethynyl and 4-methoxyphenyl groups are selective photoluminescent “light up” probes to duplex DNA with unprecedented sensibility in both spectrophotometric and spectrofluorimetric measurements.

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Bibliographic Details
Published in:Organic letters 2007-09, Vol.9 (20), p.4001-4004
Main Authors: Neto, Brenno A. D, Lapis, Alexandre A. M, Mancilha, Fabiana S, Vasconcelos, Igor B, Thum, Caroline, Basso, Luiz A, Santos, Diógenes S, Dupont, Jaïrton
Format: Article
Language:English
Subjects:
DNA - analysis
DNA - chemistry
Fluorescent Dyes - analysis
Fluorescent Dyes - chemistry
Molecular Structure
Sensitivity and Specificity
Spectrophotometry
Titrimetry
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Description
Summary:4,7-Disubstituted benzothiadiazoles containing 1-arylethynyl and 4-methoxyphenyl groups are selective photoluminescent “light up” probes to duplex DNA with unprecedented sensibility in both spectrophotometric and spectrofluorimetric measurements.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol701708y