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Modifications of Intracranial Pressure After Molecular Adsorbent Recirculating System Treatment in Patients With Acute Liver Failure: Case Reports

Abstract Cerebral dysfunction may be fatal in patients with acute liver failure (ALF); intracranial pressure (ICP) monitoring may be mandatory to direct measures to prevent further cerebral edema. Recently the introduction of dialysis with the molecular adsorbent recirculating system (MARS) has impr...

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Bibliographic Details
Published in:Transplantation proceedings 2007-07, Vol.39 (6), p.2042-2044
Main Authors: Pugliese, F, Ruberto, F, Perrella, S.M, Cappannoli, A, Bruno, K, Martelli, S, Celli, P, Summonti, D, D’Alio, A, Tosi, A, Novelli, G, Morabito, V, Poli, L, Rossi, M, Berloco, P.B, Pietropaoli, P
Format: Article
Language:English
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Summary:Abstract Cerebral dysfunction may be fatal in patients with acute liver failure (ALF); intracranial pressure (ICP) monitoring may be mandatory to direct measures to prevent further cerebral edema. Recently the introduction of dialysis with the molecular adsorbent recirculating system (MARS) has improved the outcomes among patients with ALF. The aim of this study was to evaluate ICP changes after MARS treatment among patients with ALF. Methods Three patients—14, 18 and 16 years old—were admitted to the ICU for acute liver failure induced by HBV in two cases and by acetaminophen in the other one. Because of Glasgow Coma Score (GCS)
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2007.05.061