Antioxidant Activities and Free Radical Scavenging Potential of Bauhinia microstachya (RADDI) MACBR. (Caesalpinaceae) Extracts Linked to Their Polyphenol Content

Aqueous and hydro-ethanolic extracts of Bauhinia microstachya leaves (AEBM and HEBM) were investigated for their phenolic content and phytochemical profile (by spectrophotometry and HPLC), and for their antioxidant activities and free radical scavenging potential in different in vitro systems (TRAP,...

Full description

Saved in:
Bibliographic Details
Published in:Biological & pharmaceutical bulletin 2007/08/01, Vol.30(8), pp.1488-1496
Main Authors: Silva, Evandro Gomes da, Behr, Guilherme Antonio, Zanotto-Filho, Alfeu, Lorenzi, Rodrigo, Matheus Augusto de Bittencourt Pasquali, Ravazolo, Luis Gustavo, Bordignon, Celso Luis, Jr, Silva, Francilene Amaral da, Aboy, Ana Lúcia, Bassani, Valquiria Linck, Henriques, Amélia Teresinha, Reginatto, Flávio Henrique, Dal-Pizzol, Felipe, Moreira, José Cláudio Fonseca
Format: Article
Language:English
Subjects:
antioxidant
Antioxidants - metabolism
Bauhinia - chemistry
Bauhinia microstachya
Chromans - pharmacology
Chromatography, High Pressure Liquid
Ethanol
Flavonoids - chemistry
Flavonoids - pharmacology
Free Radical Scavengers - pharmacology
HPLC analysis
Hydroxyl Radical - metabolism
in vitro system
Luminescence
Nitric Oxide - metabolism
phenolic compound
Phenols - chemistry
Phenols - pharmacology
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Leaves - chemistry
Polyphenols
Solvents
Spectrophotometry, Ultraviolet
Superoxides - metabolism
Thiobarbituric Acid Reactive Substances - metabolism
Water
Xanthine Oxidase - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aqueous and hydro-ethanolic extracts of Bauhinia microstachya leaves (AEBM and HEBM) were investigated for their phenolic content and phytochemical profile (by spectrophotometry and HPLC), and for their antioxidant activities and free radical scavenging potential in different in vitro systems (TRAP, TEAC, TBARS, nitric oxide, superoxide and hydroxyl radical). HEBM presented a 27.4% higher content of phenolics when compared to AEBM and a distinct phytochemical profile was observed. Our work suggests that both extracts have potent antioxidant activities and that their antioxidant capacity and efficiency vary according to the radical-generating system. In general, HEBM was more effective than AEBM in avoiding ROS-generating damage and in scavenging the various radicals formed. Nevertheless, when results were normalized to total phenolic content, a different profile of antioxidant activities and free radical scavenging potential was observed, particularly against oxidative lipid damage and superoxide radical. B. microstachya extracts may be considered an interesting source of natural antioxidants as well as other phenolic-rich plants.
ISSN:0918-6158
1347-5215
DOI:10.1248/bpb.30.1488