Small remnant liver volume after right lobe living donor hepatectomy

Right lobe living donor liver transplantation has become a viable option for adult patients with end-stage liver disease, however, the safety of the donor is of paramount importance. One of the key factors in donor safety is ensuring adequate donor remnant liver volume. We retrospectively examined d...

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Bibliographic Details
Published in:Surgery 2006-11, Vol.140 (5), p.749-755
Main Authors: Ibrahim, Salleh, Chen, Chao-Long, Wang, Chih-Chi, Wang, Shih-Ho, Lin, Chih-Che, Liu, Yeuh-Wei, Yang, Chin-Hsiang, Yong, Chee-Chien, Concejero, Allan, Cheng, Yu-Fan
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Critical Care - utilization
Fatty Liver - epidemiology
Female
General aspects
Hepatectomy - adverse effects
Humans
Length of Stay
Liver - pathology
Liver - physiopathology
Liver Transplantation - methods
Liver Transplantation - pathology
Liver, biliary tract, pancreas, portal circulation, spleen
Living Donors
Male
Medical sciences
Middle Aged
Organ Size
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the digestive system
Tissue and Organ Harvesting - adverse effects
Tomography, Spiral Computed
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Summary:Right lobe living donor liver transplantation has become a viable option for adult patients with end-stage liver disease, however, the safety of the donor is of paramount importance. One of the key factors in donor safety is ensuring adequate donor remnant liver volume. We retrospectively examined donors who had less than 30% remnant liver volume after right graft procurement. Eighty-six right lobe living donor transplants were carried out in Chang Gung Memorial Hospital, Kaohsiung Medical Center, from January 1999 to December 2004. Eight donors had less than 30% remnant liver volume (Group 1) after graft procurement and 78 donors had remnant liver volume greater than 30% (Group 2). There were no differences in donor characteristics, types of graft, operative parameters, and post-operative liver and renal function as well as liver volume at 6 months post-donation between the 2 groups. The graft weight obtained in Group 1 donors was significantly greater compared with that from Group 2 ( P < .005). The overall donor complication rate was 6.98%, and all the complications occurred among group 2 donors. The judicious use of donors with less than 30% remnant liver volume is safe as a last resort.
ISSN:0039-6060
1532-7361
DOI:10.1016/j.surg.2006.02.019