SEN virus infection among patients on maintenance hemodialysis in southern Taiwan

The prevalence and clinical significance of two SEN virus (SENV) strains, SENV-D and SENV-H, was investigated among patients on maintenance hemodialysis in southern Taiwan. Sera from 99 uremic patients were tested for alanine aminotransferase (ALT), hepatitis B surface antigen (HBsAg), hepatitis C v...

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Bibliographic Details
Published in:The Journal of infection 2005-08, Vol.51 (2), p.110-115
Main Authors: Dai, Chia-Yen, Chuang, Wan-Long, Chang, Wen-Yu, Chen, Shinn-Cherng, Sung, Ming-Hsing, Hsieh, Ming-Yen, Lin, Zu-Yau, Hsieh, Ming-Yuh, Wang, Liang-Yen, Tsai, Jung-Fa, Yu, Ming-Lung
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Aged
Alanine aminotransferase
Alanine Transaminase - blood
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Case-Control Studies
DNA Virus Infections - epidemiology
DNA Virus Infections - virology
DNA, Viral - blood
Emergency and intensive care: renal failure. Dialysis management
Female
Hemodialysis
Hepatitis C virus
Humans
Infectious diseases
Intensive care medicine
Linear Models
Male
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Polymerase chain reaction
Polymerase Chain Reaction - methods
Prevalence
Renal Dialysis - statistics & numerical data
Renal failure
SEN virus
Taiwan - epidemiology
Torque teno virus - classification
Uremia - complications
Uremia - therapy
Viremia - epidemiology
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Summary:The prevalence and clinical significance of two SEN virus (SENV) strains, SENV-D and SENV-H, was investigated among patients on maintenance hemodialysis in southern Taiwan. Sera from 99 uremic patients were tested for alanine aminotransferase (ALT), hepatitis B surface antigen (HBsAg), hepatitis C virus antibody (anti-HCV), and SENV-D and -H DNA. Sera from 120 healthy blood donors were tested as a control group. Of the 99 patients, 24.2 and 7.1% were positive for anti-HCV and HBsAg, respectively, and the prevalence of SENV-D and/or -H (SENV-D/H), SENV-D and SENV-H DNA was 61.6, 46.5 and 27.3%, which was significantly higher than for donors (23.3, 18.3, and 5.8%, respectively; all P
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2004.10.007