Loading…
Sleep disturbance in mild to moderate Alzheimer's disease
To determine the prevalence of sleep disturbance in a memory clinic population of Alzheimer's disease (AD) patients and identify its clinical correlates. Data from 215 attendees at a memory clinic, who were diagnosed with Alzheimer's disease, were examined. This included data from cognitiv...
Saved in:
| Published in: | Sleep medicine 2005-07, Vol.6 (4), p.347-352 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c423t-be85d3b523d42ad50ba76e848ea17282b828e1935861750b02e9b021ad88a0043 |
|---|---|
| cites | |
| container_end_page | 352 |
| container_issue | 4 |
| container_start_page | 347 |
| container_title | Sleep medicine |
| container_volume | 6 |
| creator | Moran, Maria Lynch, C.A. Walsh, C. Coen, R. Coakley, D. Lawlor, B.A. |
| description | To determine the prevalence of sleep disturbance in a memory clinic population of Alzheimer's disease (AD) patients and identify its clinical correlates.
Data from 215 attendees at a memory clinic, who were diagnosed with Alzheimer's disease, were examined. This included data from cognitive, functional and neuropsychological assessments. Sleep disturbance was determined using the question about diurnal rhythm disturbance on the BEHAVE-AD questionnaire. Two groups, with and without sleep disturbance, were compared. Group differences were analysed using univariate analysis and stepwise logistic regression analysis.
The prevalence of sleep disturbance in this sample was 24.5%. The BEHAVE-AD ‘aggressiveness’ (
P=0.009) and ‘global rating’ (
P=0.029) (a measure of global impact of behavioural disturbance) were found to be significant predictors of sleep disturbance in AD.
Sleep disturbance in AD is associated with other behavioural symptoms, notably aggressiveness. Sleep disturbance in AD has significant impact on the patient and/or caregiver. Consideration of co-morbid behavioural symptoms may aid the clinician in choosing a suitable treatment for sleep disturbance in AD. |
| doi_str_mv | 10.1016/j.sleep.2004.12.005 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67971083</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1389945704002254</els_id><sourcerecordid>67971083</sourcerecordid><originalsourceid>FETCH-LOGICAL-c423t-be85d3b523d42ad50ba76e848ea17282b828e1935861750b02e9b021ad88a0043</originalsourceid><addsrcrecordid>eNp9kE1LxDAQhoMo7rr6CwTpSU-tmaRp0oOHZfELFjyo55A2s5il3a5JK7i_3tRd8OYlE5hn3mEeQi6BZkChuF1noUHcZozSPAOWUSqOyBSUVKkQtDiOf67KtMyFnJCzENaUggSVn5IJiFIqAXJKytcxI7Eu9IOvzKbGxG2S1jU26buk7Sx602Myb3Yf6Fr0N2Fk0QQ8Jycr0wS8ONQZeX-4f1s8pcuXx-fFfJnWOeN9WqESlleCcZszYwWtjCxQ5QoNSKZYpZhCKLlQBcjYpQzL-ICxSpl4GZ-R633u1nefA4Zety7U2DRmg90QdCFLCVTxCPI9WPsuBI8rvfWuNf5bA9WjMb3Wv8b0aEwD09FYnLo6xA9Vi_Zv5qAoAnd7AOORXw69DrXDKMo6j3Wvbef-XfADDlh8CA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67971083</pqid></control><display><type>article</type><title>Sleep disturbance in mild to moderate Alzheimer's disease</title><source>ScienceDirect Freedom Collection</source><creator>Moran, Maria ; Lynch, C.A. ; Walsh, C. ; Coen, R. ; Coakley, D. ; Lawlor, B.A.</creator><creatorcontrib>Moran, Maria ; Lynch, C.A. ; Walsh, C. ; Coen, R. ; Coakley, D. ; Lawlor, B.A.</creatorcontrib><description>To determine the prevalence of sleep disturbance in a memory clinic population of Alzheimer's disease (AD) patients and identify its clinical correlates.
Data from 215 attendees at a memory clinic, who were diagnosed with Alzheimer's disease, were examined. This included data from cognitive, functional and neuropsychological assessments. Sleep disturbance was determined using the question about diurnal rhythm disturbance on the BEHAVE-AD questionnaire. Two groups, with and without sleep disturbance, were compared. Group differences were analysed using univariate analysis and stepwise logistic regression analysis.
The prevalence of sleep disturbance in this sample was 24.5%. The BEHAVE-AD ‘aggressiveness’ (
P=0.009) and ‘global rating’ (
P=0.029) (a measure of global impact of behavioural disturbance) were found to be significant predictors of sleep disturbance in AD.
Sleep disturbance in AD is associated with other behavioural symptoms, notably aggressiveness. Sleep disturbance in AD has significant impact on the patient and/or caregiver. Consideration of co-morbid behavioural symptoms may aid the clinician in choosing a suitable treatment for sleep disturbance in AD.</description><identifier>ISSN: 1389-9457</identifier><identifier>EISSN: 1878-5506</identifier><identifier>DOI: 10.1016/j.sleep.2004.12.005</identifier><identifier>PMID: 15978517</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Aged ; Aggression ; Alzheimer Disease - diagnosis ; Alzheimer Disease - epidemiology ; Alzheimer's disease ; BEHAVE-AD ; Caregiver burden ; Caregivers ; Cognition Disorders - diagnosis ; Cost of Illness ; Dementia ; Female ; Humans ; Male ; Neuropsychological Tests ; Prevalence ; Severity of Illness Index ; Sleep disturbance ; Sleep Wake Disorders - diagnosis ; Sleep Wake Disorders - epidemiology</subject><ispartof>Sleep medicine, 2005-07, Vol.6 (4), p.347-352</ispartof><rights>2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-be85d3b523d42ad50ba76e848ea17282b828e1935861750b02e9b021ad88a0043</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15978517$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moran, Maria</creatorcontrib><creatorcontrib>Lynch, C.A.</creatorcontrib><creatorcontrib>Walsh, C.</creatorcontrib><creatorcontrib>Coen, R.</creatorcontrib><creatorcontrib>Coakley, D.</creatorcontrib><creatorcontrib>Lawlor, B.A.</creatorcontrib><title>Sleep disturbance in mild to moderate Alzheimer's disease</title><title>Sleep medicine</title><addtitle>Sleep Med</addtitle><description>To determine the prevalence of sleep disturbance in a memory clinic population of Alzheimer's disease (AD) patients and identify its clinical correlates.
Data from 215 attendees at a memory clinic, who were diagnosed with Alzheimer's disease, were examined. This included data from cognitive, functional and neuropsychological assessments. Sleep disturbance was determined using the question about diurnal rhythm disturbance on the BEHAVE-AD questionnaire. Two groups, with and without sleep disturbance, were compared. Group differences were analysed using univariate analysis and stepwise logistic regression analysis.
The prevalence of sleep disturbance in this sample was 24.5%. The BEHAVE-AD ‘aggressiveness’ (
P=0.009) and ‘global rating’ (
P=0.029) (a measure of global impact of behavioural disturbance) were found to be significant predictors of sleep disturbance in AD.
Sleep disturbance in AD is associated with other behavioural symptoms, notably aggressiveness. Sleep disturbance in AD has significant impact on the patient and/or caregiver. Consideration of co-morbid behavioural symptoms may aid the clinician in choosing a suitable treatment for sleep disturbance in AD.</description><subject>Aged</subject><subject>Aggression</subject><subject>Alzheimer Disease - diagnosis</subject><subject>Alzheimer Disease - epidemiology</subject><subject>Alzheimer's disease</subject><subject>BEHAVE-AD</subject><subject>Caregiver burden</subject><subject>Caregivers</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cost of Illness</subject><subject>Dementia</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Neuropsychological Tests</subject><subject>Prevalence</subject><subject>Severity of Illness Index</subject><subject>Sleep disturbance</subject><subject>Sleep Wake Disorders - diagnosis</subject><subject>Sleep Wake Disorders - epidemiology</subject><issn>1389-9457</issn><issn>1878-5506</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAQhoMo7rr6CwTpSU-tmaRp0oOHZfELFjyo55A2s5il3a5JK7i_3tRd8OYlE5hn3mEeQi6BZkChuF1noUHcZozSPAOWUSqOyBSUVKkQtDiOf67KtMyFnJCzENaUggSVn5IJiFIqAXJKytcxI7Eu9IOvzKbGxG2S1jU26buk7Sx602Myb3Yf6Fr0N2Fk0QQ8Jycr0wS8ONQZeX-4f1s8pcuXx-fFfJnWOeN9WqESlleCcZszYwWtjCxQ5QoNSKZYpZhCKLlQBcjYpQzL-ICxSpl4GZ-R633u1nefA4Zety7U2DRmg90QdCFLCVTxCPI9WPsuBI8rvfWuNf5bA9WjMb3Wv8b0aEwD09FYnLo6xA9Vi_Zv5qAoAnd7AOORXw69DrXDKMo6j3Wvbef-XfADDlh8CA</recordid><startdate>20050701</startdate><enddate>20050701</enddate><creator>Moran, Maria</creator><creator>Lynch, C.A.</creator><creator>Walsh, C.</creator><creator>Coen, R.</creator><creator>Coakley, D.</creator><creator>Lawlor, B.A.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050701</creationdate><title>Sleep disturbance in mild to moderate Alzheimer's disease</title><author>Moran, Maria ; Lynch, C.A. ; Walsh, C. ; Coen, R. ; Coakley, D. ; Lawlor, B.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-be85d3b523d42ad50ba76e848ea17282b828e1935861750b02e9b021ad88a0043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Aggression</topic><topic>Alzheimer Disease - diagnosis</topic><topic>Alzheimer Disease - epidemiology</topic><topic>Alzheimer's disease</topic><topic>BEHAVE-AD</topic><topic>Caregiver burden</topic><topic>Caregivers</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cost of Illness</topic><topic>Dementia</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Neuropsychological Tests</topic><topic>Prevalence</topic><topic>Severity of Illness Index</topic><topic>Sleep disturbance</topic><topic>Sleep Wake Disorders - diagnosis</topic><topic>Sleep Wake Disorders - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moran, Maria</creatorcontrib><creatorcontrib>Lynch, C.A.</creatorcontrib><creatorcontrib>Walsh, C.</creatorcontrib><creatorcontrib>Coen, R.</creatorcontrib><creatorcontrib>Coakley, D.</creatorcontrib><creatorcontrib>Lawlor, B.A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Sleep medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moran, Maria</au><au>Lynch, C.A.</au><au>Walsh, C.</au><au>Coen, R.</au><au>Coakley, D.</au><au>Lawlor, B.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sleep disturbance in mild to moderate Alzheimer's disease</atitle><jtitle>Sleep medicine</jtitle><addtitle>Sleep Med</addtitle><date>2005-07-01</date><risdate>2005</risdate><volume>6</volume><issue>4</issue><spage>347</spage><epage>352</epage><pages>347-352</pages><issn>1389-9457</issn><eissn>1878-5506</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>To determine the prevalence of sleep disturbance in a memory clinic population of Alzheimer's disease (AD) patients and identify its clinical correlates.
Data from 215 attendees at a memory clinic, who were diagnosed with Alzheimer's disease, were examined. This included data from cognitive, functional and neuropsychological assessments. Sleep disturbance was determined using the question about diurnal rhythm disturbance on the BEHAVE-AD questionnaire. Two groups, with and without sleep disturbance, were compared. Group differences were analysed using univariate analysis and stepwise logistic regression analysis.
The prevalence of sleep disturbance in this sample was 24.5%. The BEHAVE-AD ‘aggressiveness’ (
P=0.009) and ‘global rating’ (
P=0.029) (a measure of global impact of behavioural disturbance) were found to be significant predictors of sleep disturbance in AD.
Sleep disturbance in AD is associated with other behavioural symptoms, notably aggressiveness. Sleep disturbance in AD has significant impact on the patient and/or caregiver. Consideration of co-morbid behavioural symptoms may aid the clinician in choosing a suitable treatment for sleep disturbance in AD.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>15978517</pmid><doi>10.1016/j.sleep.2004.12.005</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1389-9457 |
| ispartof | Sleep medicine, 2005-07, Vol.6 (4), p.347-352 |
| issn | 1389-9457 1878-5506 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67971083 |
| source | ScienceDirect Freedom Collection |
| subjects | Aged Aggression Alzheimer Disease - diagnosis Alzheimer Disease - epidemiology Alzheimer's disease BEHAVE-AD Caregiver burden Caregivers Cognition Disorders - diagnosis Cost of Illness Dementia Female Humans Male Neuropsychological Tests Prevalence Severity of Illness Index Sleep disturbance Sleep Wake Disorders - diagnosis Sleep Wake Disorders - epidemiology |
| title | Sleep disturbance in mild to moderate Alzheimer's disease |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-21T16%3A51%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sleep%20disturbance%20in%20mild%20to%20moderate%20Alzheimer's%20disease&rft.jtitle=Sleep%20medicine&rft.au=Moran,%20Maria&rft.date=2005-07-01&rft.volume=6&rft.issue=4&rft.spage=347&rft.epage=352&rft.pages=347-352&rft.issn=1389-9457&rft.eissn=1878-5506&rft_id=info:doi/10.1016/j.sleep.2004.12.005&rft_dat=%3Cproquest_cross%3E67971083%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c423t-be85d3b523d42ad50ba76e848ea17282b828e1935861750b02e9b021ad88a0043%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=67971083&rft_id=info:pmid/15978517&rfr_iscdi=true |