Neurobrucellosis mimicking cerebral tumor: case report and literature review

We are reporting a case of neurobrucellosis that was clinically and radiologically indistinguishable from a cerebral tumor. The histological diagnosis was granulomatous encephalitis. The diagnosis was established by enzyme-linked immunosorbent assay (ELISA), detecting high levels of Ig G and Ig M Br...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2006-06, Vol.108 (4), p.404-406
Main Authors: Miguel, Pilar San, Fernández, Gabriel, Vasallo, Francisco J., Hortas, Mario, Lorenzo, José Ramón, Rodríguez, Irene, Ortiz-Rey, José Antonio, Antón, Iosu
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Brain - microbiology
Brain - pathology
Brain - surgery
Brain Neoplasms - diagnosis
Brucellosis
Brucellosis - diagnosis
Brucellosis - microbiology
Brucellosis - surgery
Cranial computed tomography
Diagnosis, Differential
Disease
Encephalitis
Epidemiology
Female
Granulomatous encephalitis
Humans
Magnetic resonance
Magnetic Resonance Imaging
Marine mammals
Medical sciences
Neurobrucellosis
Neurology
Neurosurgery
Neurosurgical Procedures - methods
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tomography, X-Ray Computed
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Summary:We are reporting a case of neurobrucellosis that was clinically and radiologically indistinguishable from a cerebral tumor. The histological diagnosis was granulomatous encephalitis. The diagnosis was established by enzyme-linked immunosorbent assay (ELISA), detecting high levels of Ig G and Ig M Brucella antibodies in the serum and the cerebrospinal fluid. We suggest that patients with granulomatous encephalitis, without a clear etiological agent, should be studied for Brucella.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2004.12.015