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Rh-Catalyzed Enantioselective [2 + 2] Cycloaddition of Alkynyl Esters and Norbornene Derivatives

The enantioselective [2 + 2] cycloaddition of alkynes possessing an ester functionality and norbornene derivatives proceeded efficiently using a chiral rhodium catalyst. The chiral tri- and tetracyclic cyclobutenes were obtained in moderate to high ee.

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Bibliographic Details
Published in:Organic letters 2006-03, Vol.8 (7), p.1343-1345
Main Authors: Shibata, Takanori, Takami, Kyoko, Kawachi, Ai
Format: Article
Language:English
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Summary:The enantioselective [2 + 2] cycloaddition of alkynes possessing an ester functionality and norbornene derivatives proceeded efficiently using a chiral rhodium catalyst. The chiral tri- and tetracyclic cyclobutenes were obtained in moderate to high ee.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol060055r