Improving outcomes in depression: A focus on somatic symptoms

It is hypothesized that somatic symptom alleviation is a significant predictor of overall outcome in depressed primary care patients. Depressed primary care patients ( N=205) meeting DSM-IV-TR criteria received open-label antidepressant therapy. The primary symptom measurement tool used was the 17-i...

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Bibliographic Details
Published in:Journal of psychosomatic research 2006-03, Vol.60 (3), p.279-282
Main Authors: S. McIntyre, Roger, Konarski, Jakub Z., Mancini, Deborah A., Zurowski, Mateusz, Giacobbe, Peter, Soczynska, Joanna K., Kennedy, Sidney H.
Format: Article
Language:English
Subjects:
Adult
Antidepressant drugs
Antidepressants
Antidepressive Agents - therapeutic use
Biological and medical sciences
Depression
Depressive Disorder, Major - diagnosis
Depressive Disorder, Major - psychology
Depressive Disorder, Major - therapy
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
Male
Medical sciences
Neuropharmacology
Pain
Pharmacology. Drug treatments
Primary care
Primary Health Care - methods
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Remission
Remission Induction
Somatic
Somatic symptoms
Somatoform Disorders - diagnosis
Somatoform Disorders - psychology
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Summary:It is hypothesized that somatic symptom alleviation is a significant predictor of overall outcome in depressed primary care patients. Depressed primary care patients ( N=205) meeting DSM-IV-TR criteria received open-label antidepressant therapy. The primary symptom measurement tool used was the 17-item Hamilton Depression Rating Scale (HAMD-17), with the Montgomery–Asberg Depression Rating Scale (MADRS) and the Clinical Global Impression Improvement/Severity (CGI-I/S) used as secondary measures. As proxies for somatic symptoms, 8 items from the HAMD-17 (HAMD-S) and 3 items from the MADRS (MADRS-S) that measure somatic symptoms were identified and extracted. There was a significant correlation between improvement on the HAMD-S score and overall reduction on the MADRS total score ( r=.766, P
ISSN:0022-3999
1879-1360
DOI:10.1016/j.jpsychores.2005.09.010