Phenobarbital interactions with derivatized activated carbon surfaces

The interactions between phenobarbital and activated carbon surfaces were studied in detail in this work. This was accomplished by utilizing different reagents to manipulate the surface polar functional group compositions of different activated carbons, and determining how those modifications change...

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Bibliographic Details
Published in:Journal of colloid and interface science 2006-04, Vol.296 (1), p.79-85
Main Authors: Aburub, Aktham, Wurster, Dale Eric
Format: Article
Language:English
Subjects:
Activated carbon
Adsorbents
Borohydrides - chemistry
Carbon - chemistry
Chemistry
Exact sciences and technology
General and physical chemistry
Heat of displacement
Hydrophobic and Hydrophilic Interactions
Hydrophobic bonding
Modified Langmuir-like equation
Non-specific adsorption
Phenobarbital
Phenobarbital - chemistry
Specific adsorption
Surface physical chemistry
Surface Properties
Thermodynamics
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Summary:The interactions between phenobarbital and activated carbon surfaces were studied in detail in this work. This was accomplished by utilizing different reagents to manipulate the surface polar functional group compositions of different activated carbons, and determining how those modifications changed phenobarbital adsorption. Oxidation of an activated carbon surface caused a systematic decrease in the basal carbon surface, resulting in a concurrent systematic decrease in the non-specific adsorption of phenobarbital. Even more interesting, it was shown for the first time that chemical reduction of some of the carbonyl-containing functional groups on the activated carbon surface caused a significant increase in the specific adsorption of phenobarbital without any significant effect on the non-specific adsorption. These results support the notion that the OH groups on activated carbon surfaces are the specific adsorption sites for phenobarbital from aqueous solutions, and that the basal carbon surface is the region where non-specific adsorption takes place.
ISSN:0021-9797
1095-7103
DOI:10.1016/j.jcis.2005.08.035