Health-related quality of life measured by the UW-QoL—reference values from a general dental practice

The objective of this study was to obtain age and sex-specific reference values for the University of Washington head and neck cancer questionnaire version 4 (UW-QoLv4) and to compare this with patients with oral and oropharyngeal cancer. Cross-sectional reference data was collected from 372 patient...

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Bibliographic Details
Published in:Oral oncology 2006-03, Vol.42 (3), p.281-287
Main Authors: Rogers, S.N., O’Donnell, J.P., Williams-Hewitt, S., Christensen, J.C., Lowe, D.
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Female
Health-related quality of life
Humans
Longitudinal Studies
Male
Medical sciences
Middle Aged
Mouth Neoplasms - psychology
Oral cancer
Oropharyngeal cancer
Oropharyngeal Neoplasms - psychology
Otorhinolaryngology. Stomatology
Quality of Life
Reference Values
Surveys and Questionnaires - standards
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
UW-QoL
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Summary:The objective of this study was to obtain age and sex-specific reference values for the University of Washington head and neck cancer questionnaire version 4 (UW-QoLv4) and to compare this with patients with oral and oropharyngeal cancer. Cross-sectional reference data was collected from 372 patients in six local general dental practices, 349 of whom presented for routine appointments. Quota sampling was used to collect data for similar numbers of patients by gender by four age bands (40–49, 50–59, 60–69, 70–79 yr). The longitudinal sample consisted of 450 consecutive patients undergoing primary surgery for previously untreated oral and oropharyngeal squamous cell carcinoma presenting to the Regional Maxillofacial Unit Liverpool, between the years 1995 and 2002. At baseline the key differences were anxiety, pain, swallowing, chewing, and mood. At 1 yr there were big differences in all domains with deterioration in the oral cancer group. The difference was least notable in pain, shoulder, mood and anxiety. Reference data from a non-cancer population is very important when considering UW-QoL domains as an outcome parameter in clinical trials and also when discussing health-related quality of life outcomes with patients and their families.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2005.08.002