Comparison of Blood Glucose Values on Admission for Acute Myocardial Infarction in Patients With Versus Without Diabetes Mellitus

Previous studies have reported that acute hyperglycemia is associated with high mortality after acute myocardial infarction (AMI). However, optimal plasma glucose level may be different between diabetic and nondiabetic patients. The purpose of this study was to assess the relation between admission...

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Bibliographic Details
Published in:The American journal of cardiology 2009-09, Vol.104 (6), p.769-774
Main Authors: Ishihara, Masaharu, MD, PhD, Kojima, Sunao, MD, PhD, Sakamoto, Tomohiro, MD, PhD, Kimura, Kazuo, MD, PhD, Kosuge, Masami, MD, PhD, Asada, Yujiro, MD, PhD, Tei, Chuwa, MD, PhD, Miyazaki, Shunichi, MD, PhD, Sonoda, Masahiro, MD, PhD, Tsuchihashi, Kazufumi, MD, PhD, Yamagishi, Masakazu, MD, PhD, Shirai, Mutsunori, MD, PhD, Hiraoka, Hisatoyo, MD, PhD, Honda, Takashi, MD, PhD, Ogata, Yasuhiro, MD, PhD, Ogawa, Hisao, MD, PhD
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Blood
Cardiology. Vascular system
Cardiovascular
Comparative analysis
Coronary heart disease
Diabetes
Diabetes. Impaired glucose tolerance
Diabetic Angiopathies - blood
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Glucose
Heart
Heart attacks
Hospital Mortality
Humans
Hyperglycemia
Hyperglycemia - epidemiology
Male
Medical sciences
Middle Aged
Myocardial Infarction - blood
Myocardial Infarction - epidemiology
Myocardial Infarction - mortality
Myocarditis. Cardiomyopathies
Survival Analysis
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Summary:Previous studies have reported that acute hyperglycemia is associated with high mortality after acute myocardial infarction (AMI). However, optimal plasma glucose level may be different between diabetic and nondiabetic patients. The purpose of this study was to assess the relation between admission glucose and in-hospital mortality after AMI in patients with and without diabetes. This study consisted of 3,750 patients who were admitted to the 35 hospitals participating to the Japanese Acute Coronary Syndrome Study (JACSS) group within 48 hours after the onset of AMI. Plasma glucose was measured at the time of hospital admission. In patients without a history of diabetes, there was a linear relation between admission glucose and in-hospital mortality. Nondiabetic patients with a glucose level
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2009.04.055