Primitive neuroectodermal tumor/Ewing's sarcoma with long-term follow-up

We have reported a case of primitive neuroectodermal tumor/Ewing's sarcoma (PNET/EWS) in a 32-year-old female who had had no symptoms until the tumor was detected in a general examination after she gave birth. Chest X-ray showed a well-defined, rounded mass in the left lower lung field. Compute...

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Bibliographic Details
Published in:General thoracic and cardiovascular surgery 2005-02, Vol.53 (2), p.97-101
Main Authors: Fukushima, Mitsuhiro, Koizumi, Kiyoshi, Nakajima, Yuki, Fukuda, Yuh, Kawamoto, Masashi, Shimizu, Kazuo
Format: Article
Language:English
Subjects:
Adult
Female
Follow-Up Studies
Humans
Radiotherapy, Adjuvant
Reoperation
Sarcoma
Sarcoma, Ewing - therapy
Thoracic Neoplasms - therapy
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Summary:We have reported a case of primitive neuroectodermal tumor/Ewing's sarcoma (PNET/EWS) in a 32-year-old female who had had no symptoms until the tumor was detected in a general examination after she gave birth. Chest X-ray showed a well-defined, rounded mass in the left lower lung field. Computed tomographic scan of the chest revealed a distinct mass adjacent to the anterolateral thoracic wall. The macroscopic findings had shown a well-capsulated tumor with a stalk emanating from the thoracic wall. PNET/EWS was histologically diagnosed. The tumor was composed of atypical, small round cells. It stained positively with antibodies to the MIC2 gene product. Postoperative adjuvant radiotherapy of 50 Gy was performed. Adjuvant chemotherapies were not performed. Four years later, a small recurrent nodule in the left lung was surgically resected. Since her initial diagnosis, the patient has survived for seven years; in the three years since her second surgery, she has had no other recurrence or metastasis.
ISSN:1344-4964
1863-6705
1863-2092
1863-6713
DOI:10.1007/s11748-005-0009-7