Left ventricular mass regression after aortic valve replacement with 17-mm St Jude Medical mechanical prostheses in isolated aortic stenosis

The present study investigated the outcomes of aortic valve replacement with 17-mm mechanical prostheses in patients with isolated aortic stenosis. Between January 1997 and January 2003, 35 patients (mean age, 63.4 ± 17 years; median age, 70 years; age range, 16-84 years) underwent isolated aortic v...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of thoracic and cardiovascular surgery 2005-03, Vol.129 (3), p.512-517
Main Authors: Amarelli, Cristiano, Della Corte, Alessandro, Romano, Gianpaolo, Iasevoli, Gennaro, Dialetto, Giovanni, De Santo, Luca S., De Feo, Marisa, Torella, Michele, Scardone, Michelangelo, Cotrufo, Maurizio
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Aortic Valve Stenosis - diagnostic imaging
Aortic Valve Stenosis - pathology
Aortic Valve Stenosis - surgery
Biological and medical sciences
Cardiology. Vascular system
Endocardial and cardiac valvular diseases
Female
Heart
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation - methods
Heart Ventricles - pathology
Humans
Male
Medical sciences
Middle Aged
Orthopedic surgery
Retrospective Studies
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Treatment Outcome
Ultrasonography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The present study investigated the outcomes of aortic valve replacement with 17-mm mechanical prostheses in patients with isolated aortic stenosis. Between January 1997 and January 2003, 35 patients (mean age, 63.4 ± 17 years; median age, 70 years; age range, 16-84 years) underwent isolated aortic valve replacement with a 17-mm St Jude Medical Hemodynamic Plus (16 [45.7%] patients) or a St Jude Medical Regent prosthesis (19 [54.3%] patients). The paired Student t test or the paired Wilcoxon rank sum test were used to compare preoperative with follow-up echocardiographic measurements. Thirty-two (91.4%) patients were female, mean height was 154.4 ± 8.3 cm, mean weight was 62.2 ± 9.2 kg, and mean body surface area was 1.59 ± 0.13 m 2. The preoperative average New York Heart Association class was 2.8 ± 0.8. The mean preoperative left ventricular mass index was 135.2 ± 31 g/m 2. Preoperative echocardiography showed an average gradient of 65.7 ± 19.2 mm Hg (mean) and 103.6 ± 30.7 mm Hg (peak) and a mean indexed effective orifice area of 0.40 ± 0.1 cm 2/m 2. Echocardiographic follow-up time averaged 28.2 ± 22.7 months (range, 13-72 months). Follow-up was 100% complete (1131.7 patient-months). Hospital mortality was 8.6% (3 patients). Actuarial 5-year survival was 94.7%. The mean postoperative New York Heart Association class was 1.13 ± 0.34 ( P < .001), with 27 (87.1%) patients in class I and 4 patients in class II. A significant regression of the indexed left ventricular mass was found (postoperative mean value, 107.8 ± 22.8 g/m 2; P < .0001), despite a mean indexed effective orifice area of 0.67 ± 0.14 cm 2/m 2 (median, 0.66 cm 2/m 2). Selected patients with aortic stenosis can experience satisfactory clinical improvement and significant indexed left ventricular mass regression after aortic valve replacement with modern small-diameter bileaflet prostheses.
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2004.07.007