Anemia Is a Poor Predictor of Iron Deficiency Among Toddlers in the United States: For Heme the Bell Tolls

Many toddlers in the United States have their hemoglobin (Hb) measured periodically. Is this worthwhile? To determine if the presence of anemia correctly diagnoses iron deficiency (ID) and if the absence of anemia correctly rules out ID in young children. An analysis of data from the US National Hea...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2005-02, Vol.115 (2), p.315-320
Main Author: White, Keith C
Format: Article
Language:English
Subjects:
Anemia
Anemia - epidemiology
Anemia in children
Anemia, Iron-Deficiency - blood
Anemia, Iron-Deficiency - diagnosis
Anemia, Iron-Deficiency - ethnology
Anemias. Hemoglobinopathies
Biological and medical sciences
Child, Preschool
Diagnosis
Diseases of red blood cells
Ethnicity
General aspects
Hematologic and hematopoietic diseases
Hemoglobin
Hemoglobins - analysis
Humans
Infant
Iron
Iron - deficiency
Iron deficiency anemia
Medical diagnosis
Medical sciences
Metabolic diseases
Metals (hemochromatosis...)
Nutrition Surveys
Other metabolic disorders
Pediatric anemia
Pediatrics
Predictive Value of Tests
Preschool children
Sensitivity and Specificity
United States - epidemiology
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Summary:Many toddlers in the United States have their hemoglobin (Hb) measured periodically. Is this worthwhile? To determine if the presence of anemia correctly diagnoses iron deficiency (ID) and if the absence of anemia correctly rules out ID in young children. An analysis of data from the US National Health and Nutrition Examination Survey III (1988-1994) was performed. Subjects were children 12 to 35 months old for whom complete blood counts and cardinal measures of iron nutrition (ferritin, transferrin saturation, and free erythrocyte protoporphyrin) were reported. In the US National Health and Nutrition Examination Survey III, the prevalence of ID ranged from 6% to 18% in various subpopulations of toddlers. In the general population, the positive predictive value of Hb concentration ([Hb])
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2004-1488