Cervical Ureaplasma urealyticum colonization might be associated with increased incidence of preterm delivery in pregnant women without prophlogistic microorganisms on routine examination

Aim: We examined whether the detection of Ureaplasma urealyticum DNA in the cervix is associated with preterm labor and delivery. Methods: Eighty‐two women (23 preterm labor cases and 59 controls) with no evidence of prophlogistic microorganisms on routine microbiologic examination were enrolled for...

Full description

Saved in:
Bibliographic Details
Published in:The journal of obstetrics and gynaecology research 2005-02, Vol.31 (1), p.16-21
Main Authors: Mitsunari, Masahiro, Yoshida, Souichi, Deura, Imari, Horie, Sayako, Tsukihara, Satoru, Harada, Tasuku, Irie, Takashi, Terakawa, Naoki
Format: Article
Language:English
Subjects:
Adolescent
Adult
bacterial vaginosis
Case-Control Studies
Cervix Uteri - microbiology
DNA Primers
DNA, Bacterial - analysis
Female
Humans
Incidence
Japan - epidemiology
Obstetric Labor, Premature - epidemiology
Obstetric Labor, Premature - microbiology
Polymerase Chain Reaction
Pregnancy
preterm delivery
Ureaplasma urealyticum
Ureaplasma urealyticum - genetics
Ureaplasma urealyticum - isolation & purification
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim: We examined whether the detection of Ureaplasma urealyticum DNA in the cervix is associated with preterm labor and delivery. Methods: Eighty‐two women (23 preterm labor cases and 59 controls) with no evidence of prophlogistic microorganisms on routine microbiologic examination were enrolled for this study. U. urealyticum colonization was examined using polymerase chain reaction of cervical swabs. Results: The positivity rate of U. urealyticum DNA in preterm labor cases was significantly higher than that in the controls (87.0%vs 45.8%, P = 0.0007). Women in the U. urealyticum‐positive group more frequently delivered preterm compared with those in the negative group (36.2%vs 11.4%, P = 0.0111). In five cases that delivered preterm with histologically confirmed chorioamnionitis, U. urealyticum DNA was detected in the placenta. Conclusions: Cervical U. urealyticum colonization might be associated with preterm labor and delivery.
ISSN:1341-8076
1447-0756
DOI:10.1111/j.1447-0756.2005.00246.x