Chemical investigation and effects of the tea of Passiflora alata on biochemical parameters in rats

Passiflora alata (Passifloraceae) is a native plant from the South-America tropical forest that provides a much apreciated fruit known as “maracujá-doce”. Although tea of the leaves of Passiflora alata is used in folk medicine as a sedative and tranquilizer, there are no investigations about its eff...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2005-01, Vol.96 (3), p.371-374
Main Authors: Doyama, J.T., Rodrigues, H.G., Novelli, E.L.B., Cereda, E., Vilegas, W.
Format: Article
Language:English
Subjects:
Animals
antioxidants
Apigenin - chemistry
Apigenin - isolation & purification
Biological and medical sciences
blood chemistry
blood glucose
Blood Glucose - drug effects
blood lipids
Blood Proteins - metabolism
Body Weight - drug effects
cholesterol
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Flavones - chemistry
Flavones - isolation & purification
Flavonoids
Flavonoids - chemistry
Flavonoids - isolation & purification
General pharmacology
Glutathione Peroxidase - blood
HDL-cholesterol
leaves
Luteolin - chemistry
Luteolin - isolation & purification
Male
Medical sciences
Medicinal plant
medicinal plants
Passiflora
Passiflora alata
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
phytochemicals
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Leaves - chemistry
Rats
Rats, Wistar
Saponins
Saponins - chemistry
Saponins - isolation & purification
Superoxide Dismutase - blood
tea
traditional medicine
Triglycerides - blood
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Summary:Passiflora alata (Passifloraceae) is a native plant from the South-America tropical forest that provides a much apreciated fruit known as “maracujá-doce”. Although tea of the leaves of Passiflora alata is used in folk medicine as a sedative and tranquilizer, there are no investigations about its effects on biochemical parameters in blood or from its major chemical composition. The purpose of this study was to evaluate the effects of the tea of the leaves of Passiflora alata on biochemical parameters (antioxidant system, glucose and cholesterol levels) and to perform a phytochemical investigation of the tea. We isolated and identified two saponins and five C-glycosylflavones derived from apigenin, luteolin and chrysoeriol.Three of them are new in this species. Passiflora alata extract was administrated orally in rats at dose of 1000 mg/kg and it was observed an increase in high-density lipoprotein level (HDL-cholesterol).
ISSN:0378-8741
1872-7573
DOI:10.1016/j.jep.2004.06.021