Bladder tumour staging: comparison of diffusion- and T2-weighted MR imaging

The aim of this work was to evaluate the clinical feasibility of diffusion-weighted (DW) MRI in detection and staging of urinary bladder tumour and to compare DW MRI with the T 2 -weighted technique. One hundred and six patients with bladder tumour were prospectively included in our study. All patie...

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Bibliographic Details
Published in:European radiology 2009-07, Vol.19 (7), p.1575-1581
Main Authors: El-Assmy, Ahmed, Abou-El-Ghar, Mohamed E., Mosbah, Ahmed, El-Nahas, Ahmed R., Refaie, Huda F., Hekal, Ihab A., El-Diasty, Tarek, Ibrahiem, El Housseiny
Format: Article
Language:English
Subjects:
Aged
Diagnostic Radiology
Diffusion Magnetic Resonance Imaging - methods
Feasibility Studies
Female
Humans
Imaging
Internal Medicine
Interventional Radiology
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Staging
Neuroradiology
Radiology
Reproducibility of Results
Sensitivity and Specificity
Ultrasound
Urinary Bladder Neoplasms - diagnosis
Urogenital
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Summary:The aim of this work was to evaluate the clinical feasibility of diffusion-weighted (DW) MRI in detection and staging of urinary bladder tumour and to compare DW MRI with the T 2 -weighted technique. One hundred and six patients with bladder tumour were prospectively included in our study. All patients were evaluated with MR imaging. We started with axial T 2 -weighted high resolution MR of the urinary bladder, then DW MRI. Two radiologists independently interpreted the MR images, and discrepancies were resolved by consensus. The accuracy of DW MRI in staging of bladder tumour was evaluated using the final histopathological findings. In DW imaging (DWI) staging accuracy was 63.6% and 69.6% in differentiating superficial from invasive tumours and organ-confined from non-organ-confined tumours, respectively. On a stage by a stage basis, DWI accuracy was 63.6% (21/33), 75.7% (25/33), 93.7% (30/32) and 87.5% (7/8) for stages T1, T2, T3 and T4, respectively. In the T 2 -weighted technique, the overall staging accuracy was only 39.6% and accuracy for differentiating superficial from invasive tumours and organ-confined from non-organ-confined tumours was 6.1% and 15.1%, respectively. DW is superior to T 2 -weighted MRI in staging of organ-confined tumours ( ≤ T2) and both techniques are comparable in the evaluation of higher-stage tumours.
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-009-1340-7