BODIL: a molecular modeling environment for structure-function analysis and drug design

BODIL is a molecular modeling environment geared to help the user to quickly identify key features of proteins critical to molecular recognition, especially (1) in drug discovery applications, and (2) to understand the structural basis for function. The program incorporates state-of-the-art graphics...

Full description

Saved in:
Bibliographic Details
Published in:Journal of computer-aided molecular design 2004-06, Vol.18 (6), p.401-419
Main Authors: Lehtonen, Jukka V, Still, Dan-Johan, Rantanen, Ville-V, Ekholm, Jan, Björklund, Dag, Iftikhar, Zuhair, Huhtala, Mikko, Repo, Susanna, Jussila, Antti, Jaakkola, Jussi, Pentikäinen, Olli, Nyrönen, Tommi, Salminen, Tiina, Gyllenberg, Mats, Johnson, Mark S
Format: Article
Language:English
Subjects:
Algorithms
CAD
Computer aided design
Computer Graphics
Computer Simulation
Drug Design
Models, Molecular
Protein Conformation
Proteins
Sequence Alignment - statistics & numerical data
Software
Static Electricity
Structure-Activity Relationship
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:BODIL is a molecular modeling environment geared to help the user to quickly identify key features of proteins critical to molecular recognition, especially (1) in drug discovery applications, and (2) to understand the structural basis for function. The program incorporates state-of-the-art graphics, sequence and structural alignment methods, among other capabilities needed in modern structure-function-drug target research. BODIL has a flexible design that allows on-the-fly incorporation of new modules, has intelligent memory management, and fast multi-view graphics. A beta version of BODIL and an accompanying tutorial are available at http://www.abo.fi/fak/mnf/bkf/research/johnson/bodil.html.
ISSN:0920-654X
1573-4951
DOI:10.1007/s10822-004-3752-4