Effects of septoplasty and septal deviation on nasal mucociliary clearance

Summary To evaluate the effect of septal pathology and surgery on nasal mucociliary clearance. A radioisotope method was used to measure the velocity of nasal mucociliary transport. Nasal mucociliary clearance was measured before and after septal surgery using technetium−99 m macroaggregated albumin...

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Bibliographic Details
Published in:International journal of clinical practice (Esher) 2004-12, Vol.58 (12), p.1108-1111
Main Authors: Uslu, H., Uslu, C., Varoglu, E., Demirci, M., Seven, B.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Female
General aspects
Humans
Male
Measurement
Medical sciences
mucociliary clearance
Mucociliary Clearance - physiology
Mucous membrane
Nasal Septum - abnormalities
Nasal Septum - diagnostic imaging
Nasal Septum - surgery
Nose
Preoperative Care - methods
Radioisotopes
Radionuclide Imaging
Radiopharmaceuticals
rhinoscintigraphy
Septoplasty
Surgery
Technetium Tc 99m Aggregated Albumin
Treatment Outcome
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Summary:Summary To evaluate the effect of septal pathology and surgery on nasal mucociliary clearance. A radioisotope method was used to measure the velocity of nasal mucociliary transport. Nasal mucociliary clearance was measured before and after septal surgery using technetium−99 m macroaggregated albumin. Fifteen patients (mean age: 20 ± 8 years; 11 males, four females) were studied pre‐operatively, but scintigraphy could be repeated only in 10 patients, 2 months after surgery. A group of 10 healthy volunteers were also studied. The clearance values obtained from the pre‐operative period (26.25 ± 9.45 min) were significantly higher than those of the post‐operative period (15.05 ± 6.35 min). The values obtained of control group (13.30 ± 3.15 min) were not significantly different from the post‐operative values of the patient group. Septal deviation affects the mucociliary activity. It is improved by surgery. This study showed that nasal septal deviation reduced the nasal mucociliary activity, and this can easily evaluated with scintigraphy.
ISSN:1368-5031
1742-1241
DOI:10.1111/j.1742-1241.2004.00205.x