Gender Differences in Stroke Incidence and Poststroke Disability in the Framingham Heart Study

Stroke is emerging as a major public health problem for women, as it is for men. Controversy persists regarding gender differences in stroke incidence, severity, and poststroke disability. Participants in the Framingham Original (n=5119; 2829 women) and Offspring (n=4957, 2565 women) cohorts who wer...

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Bibliographic Details
Published in:Stroke (1970) 2009-04, Vol.40 (4), p.1032-1037
Main Authors: PETREA, Rodica E, BEISER, Alexa S, SESHADRI, Sudha, KELLY-HAYES, Margaret, KASE, Carlos S, WOLF, Philip A
Format: Article
Language:English
Subjects:
Age Distribution
Aged
Aged, 80 and over
Biological and medical sciences
Comorbidity
Disability Evaluation
Disabled Persons - statistics & numerical data
Female
Follow-Up Studies
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Humans
Incidence
Institutionalization - statistics & numerical data
Male
Massachusetts - epidemiology
Medical sciences
Middle Aged
Nervous system (semeiology, syndromes)
Neurology
Risk Factors
Severity of Illness Index
Sex Characteristics
Sex Distribution
Stroke - epidemiology
Stroke - physiopathology
Vascular diseases and vascular malformations of the nervous system
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Summary:Stroke is emerging as a major public health problem for women, as it is for men. Controversy persists regarding gender differences in stroke incidence, severity, and poststroke disability. Participants in the Framingham Original (n=5119; 2829 women) and Offspring (n=4957, 2565 women) cohorts who were 45 years and stroke-free were followed to first incident stroke. Gender-specific outcome measures were adjusted for the Framingham Stroke Risk Profile components. We observed 1136 incident strokes (638 in women) over 56 years of follow-up. Women were significantly (P
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.108.542894