Levonorgestrel-releasing intrauterine system vs. endometrial thermal ablation for menorrhagia

OBJECTIVE: To evaluate the efficacy of a Levonorgestrel-releasing Intrauterine System (LNG-IUS) in controlling menorrhagia in comparison with endometrial thermal rollerball ablation. DESIGN: Seventy-nine consecutive patients with menorrhagia underwent either LNG-IUS insertion (n=42) or hysteroscopic...

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Bibliographic Details
Published in:Hormones (Athens, Greece) Greece), 2009-01, Vol.8 (1), p.60-64
Main Authors: Theodoridis, Theodoros D., Zepiridis, Leonidas, Zafrakas, Menelaos, Grimbizis, Grigoris, Tantsis, Antonios, Kyrou, Dimitra, Bontis, John N.
Format: Article
Language:English
Subjects:
Endocrinology
Endometrial Ablation Techniques - economics
Female
Humans
Intrauterine Devices, Medicated - economics
Levonorgestrel - administration & dosage
Levonorgestrel - therapeutic use
Medicine
Medicine & Public Health
Menorrhagia - drug therapy
Metabolic Diseases
Prospective Studies
Research Paper
Uterine Hemorrhage - drug therapy
Young Adult
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Summary:OBJECTIVE: To evaluate the efficacy of a Levonorgestrel-releasing Intrauterine System (LNG-IUS) in controlling menorrhagia in comparison with endometrial thermal rollerball ablation. DESIGN: Seventy-nine consecutive patients with menorrhagia underwent either LNG-IUS insertion (n=42) or hysteroscopical endometrial thermal rollerball ablation (n=37) in a prospective, observational, comparative study. Women reported duration of uterine bleeding in days prior to, and six and 12 months after each intervention. Prior to each intervention, endometrial, cervical or other pathological conditions of the genital tract were excluded. GnRH analogues for endometrial suppression were given for ten weeks before endometrial ablation but not prior to LNG-IUS insertion. RESULTS: There were no differences in duration of uterine bleeding before each intervention in the two groups. The duration of uterine bleeding was lower in the LNG-IUS group as compared with endometrial ablation at six (p
ISSN:1109-3099
2520-8721
DOI:10.14310/horm.2002.1223