Isolation of an adenovirus and an adeno-associated virus from goat kids with enteritis

A dairy goat operation in Minnesota experienced a sudden, markedly increased mortality among its neonatal goats. Approximately 60 of 130 kids (46%) died. The animals had diarrhea and dyspnea of 1-2 days duration before death. Necropsy of 4 goat kids revealed marked, acute, catarrhal enteritis and fi...

Full description

Saved in:
Bibliographic Details
Published in:Journal of veterinary diagnostic investigation 2004-09, Vol.16 (5), p.461-464
Main Authors: Olson, E.J, Haskell, S.R.R, Frank, R.K, Lehmkuhl, H.D, Hobbs, L.A, Warg, J.V, Landgraf, J.G, Wunschmann, A
Format: Article
Language:English
Subjects:
Adenoviridae
Adenoviridae - isolation & purification
Adenoviridae - ultrastructure
Adenoviridae Infections - epidemiology
Adenoviridae Infections - veterinary
Adenoviridae Infections - virology
Animal Husbandry - methods
Animals
Animals, Suckling
dairy animals
Dependovirus - isolation & purification
Dependovirus - ultrastructure
Disease Outbreaks - veterinary
enteritis
Enteritis - pathology
Enteritis - veterinary
Enteritis - virology
Feces - virology
Female
goat diseases
Goat Diseases - pathology
Goat Diseases - virology
Goats
Male
Mannheimia haemolytica - isolation & purification
Microscopy, Electron, Transmission - veterinary
Minnesota - epidemiology
neonates
Ovine adeno-associated virus
Ovine adeno-associated virus 2
Parvoviridae Infections - epidemiology
Parvoviridae Infections - veterinary
Parvoviridae Infections - virology
Pasteurellaceae Infections - microbiology
Pasteurellaceae Infections - veterinary
Pleuropneumonia - microbiology
Pleuropneumonia - pathology
Pleuropneumonia - veterinary
signs and symptoms (animals and humans)
viral diseases of animals and humans
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A dairy goat operation in Minnesota experienced a sudden, markedly increased mortality among its neonatal goats. Approximately 60 of 130 kids (46%) died. The animals had diarrhea and dyspnea of 1-2 days duration before death. Necropsy of 4 goat kids revealed marked, acute, catarrhal enteritis and fibrinous pleuropneumonia. Mannheimia haemolytica was isolated from the lungs. Basophilic inclusion bodies filling the entire nucleus were present in enterocytes of the ileum of 3 goats. Adenoviral particles were detected in the feces by electron microscopy and adenovirus was subsequently isolated from the intestinal content together with a parvo-like virus (dependovirus). Morphology, physicochemical characteristics, and neutralization tests indicated that the adenovirus resembled ovine adenovirus-2 (OAdV-2). However, the PstI restriction endonuclease pattern produced by the goat adenovirus was distinct from that of OAdV-2. This is the first report of enteritis in goats with an adenovirus antigenically related to OAdV-2 and with a parvo-like dependovirus.
ISSN:1040-6387
1943-4936
DOI:10.1177/104063870401600518