Usefulness of catheter tip culture in the diagnosis of neonatal infections

To determine the number of colony-forming units (CFU) that best correlates with catheter-related infections (CRI) in newborns. This was a prospective study of semiquantitative cultures of catheter tips obtained from newborns in the neonatal unit at Faculdade de Medicina de Botucatu, state of São Pau...

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Bibliographic Details
Published in:Jornal de pediatria 2009-01, Vol.85 (1), p.80-83
Main Authors: Marconi, Camila, Cunha, Maria de Lourdes Ribeiro de Souza da, Lyra, João C, Bentlin, Maria R, Batalha, Jackson E N, Sugizaki, Maria Fátima, Corrente, José E, Rugolo, Lígia M S S
Format: Article
Language:eng ; por
Subjects:
Catheter-Related Infections - diagnosis
Catheter-Related Infections - microbiology
Catheterization - instrumentation
Colony Count, Microbial
Culture Media
Epidemiologic Methods
Humans
Infant, Newborn
Staphylococcal Infections - microbiology
Staphylococcus epidermidis - isolation & purification
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Summary:To determine the number of colony-forming units (CFU) that best correlates with catheter-related infections (CRI) in newborns. This was a prospective study of semiquantitative cultures of catheter tips obtained from newborns in the neonatal unit at Faculdade de Medicina de Botucatu, state of São Paulo, Brazil. The microorganisms isolated from catheter and peripheral blood cultures were identified and submitted to a drug susceptibility test. The optimal cutoff point was determined by the receiver operating characteristic (ROC) curve. A total of 85 catheters obtained from 63 newborns were studied. Staphylococcus epidermidis was the predominant species in the catheters (75%). Eight of 11 (72.7%) CRI episodes were associated with coagulase-negative staphylococci, six of which were of the S. epidermidis type. ROC curve analysis indicated that the optimal cutoff point for the diagnosis of CRI was 122 CFU. The cutoff point of 122 CFU correlated best with the diagnosis of CRI in newborns.
ISSN:0021-7557
1678-4782
DOI:10.2223/JPED.1813