An efficient one-pot procedure for asymmetric bifunctionalization of 5,15-disubstituted porphyrins: a simple preparation of meso acyl-, alkoxycarbonyl-, and carbamoyl-substituted meso-formylporphyrins

An efficient one-pot procedure which converts 5,15-disubstituted porphyrins into their corresponding meso acyl-, alkoxycarbonyl-, and carbamoyl-substituted meso-formylporphyrins has been developed, where the procedure involves a sequential S(N)Ar reaction of porphyrins with PyMe(2)SiCH(2)Li, followe...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2009-01 (1), p.101-103
Main Authors: Takanami, Toshikatsu, Wakita, Atsushi, Matsumoto, Jun, Sekine, Sadashige, Suda, Kohji
Format: Article
Language:English
Subjects:
Acylation
Indicators and Reagents
Lithium Compounds - chemical synthesis
Lithium Compounds - chemistry
Oxidation-Reduction
Porphyrins - chemical synthesis
Porphyrins - chemistry
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Summary:An efficient one-pot procedure which converts 5,15-disubstituted porphyrins into their corresponding meso acyl-, alkoxycarbonyl-, and carbamoyl-substituted meso-formylporphyrins has been developed, where the procedure involves a sequential S(N)Ar reaction of porphyrins with PyMe(2)SiCH(2)Li, followed by acylation or related reactions and oxidation.
ISSN:1359-7345
1364-548X
DOI:10.1039/b817551a