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A report by Cheng et al sheds light on the surprising thrombotic side effects observed in a recent clinical trial of a new anti-inflammatory drug. The group of chemical mediators known as the eicosanoids is discussed.

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2002-04, Vol.296 (5567), p.474-475
Main Author: Vane, John R.
Format: Article
Language:English
Subjects:
Anatomy
Aspirin
Cardiovascular agents
Clinical trials
Cyclooxygenase inhibitors
Derivatives
Drugs
Eicosanoic acid
Eicosanoids
Enzymes
Evidence
Homeostasis
Human Body
Injuries
Mantle
Medical research
Medicine, Experimental
Minerals
Narcotics
Osmium
Patients
Perspectives
Physiological aspects
Platelets
Protein isoforms
Rodents
Vasoconstrictor agents
Vasoconstrictors
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Description
Summary:A report by Cheng et al sheds light on the surprising thrombotic side effects observed in a recent clinical trial of a new anti-inflammatory drug. The group of chemical mediators known as the eicosanoids is discussed.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1071702