Echocardiographic factors associated with thromboembolic events in patients with cardiac amyloidosis without atrial fibrillation

Cardiac amyloidosis (CA) is associated with various complications, and one of them are thromboembolic events (TEEs), which can significantly impact patients' quality of life. Predicting and managing the risk of these TEEs in patients without atrial fibrillation (AF) pose significant challenges,...

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Bibliographic Details
Published in:Journal of cardiology 2024-08
Main Authors: Romero, Cristhian Espinoza, Pereira, Natalia Melo, Morales, Kevin De Paula, Kerges Bueno, Bruno V., Luzuriaga, Georgina J., Egypto Rosa, Vitor E., Rissato, Joao Henrique, Hotta, Viviane T., Fernandes, Fabio
Format: Article
Language:English
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Summary:Cardiac amyloidosis (CA) is associated with various complications, and one of them are thromboembolic events (TEEs), which can significantly impact patients' quality of life. Predicting and managing the risk of these TEEs in patients without atrial fibrillation (AF) pose significant challenges, as many occur independently of AF presence. Several predictors, particularly echocardiographic ones, have been linked to an increased risk, but there is no consensus on stratification or preventive treatment. The main objective was to determine the prevalence of TEEs in a cohort of CA patients without AF and identify echocardiographic predictors. A retrospective, single-center study including confirmed CA patients. A prespecified list of variables was defined, and only patients with at least 70 % of these variables were included. Risk rates were analyzed through binary logistic regression, with a significance level set at p 
ISSN:0914-5087
1876-4738
1876-4738
DOI:10.1016/j.jjcc.2024.08.001