Effects of Peroperative Cold Ischemia Time and Anhepatic Phase in Adult Living Donor Liver Transplant Recipients: Operation Time That is Not Affected by the Anhepatic Phase But is Prolonged by Cold Ischemia Time

•Anhepatic phase does not affect the duration of surgery, and a prolonged cold ischemia time statistically increases the time of surgery.•While the results of cadaveric liver transplantation are monitored more intensively in the studies, the feature of this study is that it examines the perioperativ...

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Bibliographic Details
Published in:Transplantation proceedings 2024-07, Vol.56 (6), p.1374-1377
Main Authors: Anilir, Ender, Sönmez Topçu, Feyza, Şahin, Emrah, Oral, Alihan, Ayyildiz Civan, Hasret, Orhan Poyrazoğlu, Kürşat, Dirican, Abuzer, Ünal, Bülent
Format: Article
Language:English
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Summary:•Anhepatic phase does not affect the duration of surgery, and a prolonged cold ischemia time statistically increases the time of surgery.•While the results of cadaveric liver transplantation are monitored more intensively in the studies, the feature of this study is that it examines the perioperative phases and effects of living donor liver transplantation.•Anhepatic phase and cold ischemia time have no effect on postoperative complications and infections, mortality, and graft/patient survival. It was aimed to examine the overall role of cold ischemia time and anhepatic phase durations in terms of peroperative blood transfusion needs, hospital stay conditions and postoperative charges, and survival in recipients. One hundred forty-eight adult living donor liver transplant recipients (18 years and older) were included in the study. Whether the anhepatic phase and cold ischemia duration have an effect on the rates of surgery time, blood product transfusion, total hospital and intensive care unit stay, postoperative biliary complications, hepatic vein thrombosis, portal vein thrombosis, early postoperative bleeding, sepsis, and primary graft dysfunction. Was analyzed statistically. In addition, the effect of the anhepatic phase and cold ischemia time on graft survival was statistically examined by creating an average of the patient follow-up period. It was observed that the operation time increased statistically as the cold ischemia time increased (P = .000). No statistically significant relationship was found between other findings and cold ischemia time and anhepatic phase. Prolonged surgery time due to increased cold ischemia time may be an important finding in terms of peroperative and postoperative results of the graft.
ISSN:0041-1345
1873-2623
1873-2623
DOI:10.1016/j.transproceed.2024.02.029