Characterization of Gram-negative Bloodstream Infections in Hospitalized Australian Children and Their Clinical Outcomes

Abstract Background Gram-negative bloodstream infections (GNBSIs) more commonly occur in children with comorbidities and are increasingly associated with antimicrobial resistance. There are few large studies of GNBSIs in children that relate the clinical presentation, pathogen characteristics, and o...

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Published in:Clinical infectious diseases 2024-06
Main Authors: Wen, Sophie C H, Harris, Patrick N A, Forde, Brian, Permana, Budi, Chatfield, Mark D, Lau, Colleen L, Spurling, Geoffrey, Bauer, Michelle J, Balch, Ross, Chambers, Henry, Schlapbach, Luregn J, Clark, Julia E, Dougherty, Sonia, Blyth, Christopher C, Britton, Philip N, Clifford, Vanessa, Haeusler, Gabrielle M, McMullan, Brendan, Wadia, Ushma, Paterson, David L, Irwin, Adam D, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R, Macartney, Kristine, Crawford, Nigel W, Wood, Nicholas, Buttery, Jim, Marshall, Helen, Elliott, Elizabeth, Richmond, Peter, Carey, Emma, McMinn, Alissa, Bellamy, Karen, Hunter, Guillian, Meredith, Kathryn, Rost, Laura, Kerly, Nicole, Cook, Sara, Doran, Natasha, Francis, Laura, Heath, Christine, Finucane, Carolyn, Baik, Mehyar Khair, Lopez, Laura, Glover, Catherine
Format: Article
Language:English
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Summary:Abstract Background Gram-negative bloodstream infections (GNBSIs) more commonly occur in children with comorbidities and are increasingly associated with antimicrobial resistance. There are few large studies of GNBSIs in children that relate the clinical presentation, pathogen characteristics, and outcomes. Methods A 3-year prospective study of GNBSIs in children aged
ISSN:1058-4838
1537-6591
1537-6591
DOI:10.1093/cid/ciae341