An Ion‐Mediated Spiking Chemical Neuron based on Mott Memristor

Artificial spiking neurons capable of interpreting ionic information into electrical spikes are critical to mimic biological signaling systems. Mott memristors are attractive for constructing artificial spiking neurons due to their simple structure, low energy consumption, and rich neural dynamics....

Full description

Saved in:
Bibliographic Details
Published in:Advanced materials (Weinheim) 2024-08, Vol.36 (33), p.e2403678-n/a
Main Authors: Ren, Huihui, Li, Fanfan, Wang, Min, Liu, Guolei, Li, Dingwei, Wang, Rui, Chen, Yitong, Tang, Yingjie, Wang, Yan, Jin, Ran, Huang, Qi, Xing, Lixiang, Chen, Xiaopeng, Wang, Juan, Guo, Chengchen, Zhu, Bowen
Format: Article
Language:English
Subjects:
biohybrid interface
Biological effects
Chemical sensors
Energy consumption
ion‐mediation
Memristors
Mott memristor
Neurons
Physiological effects
Signalling systems
Spiking
spiking neuron
threshold switching
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Artificial spiking neurons capable of interpreting ionic information into electrical spikes are critical to mimic biological signaling systems. Mott memristors are attractive for constructing artificial spiking neurons due to their simple structure, low energy consumption, and rich neural dynamics. However, challenges remain in achieving ion‐mediated spiking and biohybrid‐interfacing in Mott neurons. Here, a biomimetic spiking chemical neuron (SCN) utilizing an NbOx Mott memristor and oxide field‐effect transistor‐type chemical sensor is introduced. The SCN exhibits both excitation and inhibition spiking behaviors toward ionic concentrations akin to biological neural systems. It demonstrates spiking responses across physiological and pathological Na+ concentrations (1–200 × 10−3 m). The Na+‐mediated SCN enables both frequency encoding and time‐to‐first‐spike coding schemes, illustrating the rich neural dynamics of Mott neuron. In addition, the SCN interfaced with L929 cells facilitates real‐time modulation of ion‐mediated spiking under both normal and salty cellular microenvironments. An artificial spiking chemical neuron is achieved based on transistor‐type biosensor and Mott memristor, which enables encoding ionic information in liquid environment into electrical spike trains via frequency and time‐to‐first‐spike coding schemes. The artificial neuron demonstrates rich neural dynamics with both excitation and inhibition spiking behaviors toward ionic concentrations like biological neural systems.
ISSN:0935-9648
1521-4095
1521-4095
DOI:10.1002/adma.202403678