Prospective study about the security and efficacy of treatment without antibiotic therapy of patients diagnosed with acute uncomplicated diverticulitis after launching a protocol at a tertiary hospital

[Display omitted] The main objective of our study is to analyze the results in our hospital after launching a treatment protocol without antibiotic therapy for patients diagnosed with acute uncomplicated diverticulitis. Our observational, prospective, single-center study was developed after launchin...

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Published in:Cirugia española (English ed.) 2024-09, Vol.102 (9), p.477-483
Main Authors: Correa Bonito, Alba, Cerdán Santacruz, Carlos, García del Álamo Hernández, Yaiza, Gijón Moya, Fernando, Bermejo Marcos, Elena, Rodríguez Sánchez, Ana, García Septiem, Javier, Martín Pérez, Elena
Format: Article
Language:English
Subjects:
Acute uncomplicated diverticulitis
Conservative treatment
Diverticulitis aguda no complicada
Outpatient treatment
Tratamiento ambulatorio
Tratamiento conservador
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Summary:[Display omitted] The main objective of our study is to analyze the results in our hospital after launching a treatment protocol without antibiotic therapy for patients diagnosed with acute uncomplicated diverticulitis. Our observational, prospective, single-center study was developed after launching a treatment protocol without antibiotic therapy for patients diagnosed with acute uncomplicated diverticulitis (AUD) in January 2021. The follow-up period was from January 1, 2021 to September 30, 2023. Variables evaluated by the study have included demographic and analytical variables, as well as those related to diagnosis and whether the patients needed to start antibiotic treatment, inpatient treatment, or surgical procedures. In total, 199 patients were diagnosed with AUD, 75 of whom were treated without antibiotic therapy as outpatients. Seven of these patients needed to start antibiotic treatment because of adverse evolution; none of these patients required surgical procedures. The need for inpatient treatment, urgent care, or surgical procedures is similar to the group of patients treated with antibiotics. The main risk factor of failure of outpatient treatment without antibiotic therapy identified by the study was the presence of bacteriuria at diagnosis. Our results confirm previous reports, observing that treatment without antibiotic therapy in selected patients with AUD is safe. El objetivo de nuestro estudio es analizar los resultados obtenidos en nuestro centro tras la puesta en marcha de un protocolo de tratamiento sin antibioterapia en pacientes diagnosticados de diverticulitis aguda no complicada. Se trata de un estudio observacional prospectivo unicéntrico tras la implantación de un protocolo de tratamiento sin antibioterapia en pacientes con diverticulitis aguda no complicada (DANC) en enero de 2021. El periodo de seguimiento fue desde la implantación del protocolo el 1 de enero de 2021 hasta el 30 de septiembre de 2023. Se recogieron variables demográficas, analíticas y diagnósticas de los pacientes valorados, así como si precisaron el inicio de antibioterapia, ingreso o intervención quirúrgica. 199 pacientes fueron diagnosticados de DANC, de los cuales, 75 fueron tratados de forma ambulatoria sin antibioterapia. En 7 de los casos fue preciso iniciar el tratamiento antibiótico por evolución desfavorable, sin que en ninguno de los casos fuera necesario realizar una intervención quirúrgica o drenaje percutáneo urgente. Los resultados, en térmi
ISSN:2173-5077
2173-5077
DOI:10.1016/j.cireng.2024.04.019