Distributions of candidate vaccine Targets, virulence Factors, and resistance features of invasive group B Streptococcus using Whole-Genome Sequencing: A Multicenter, population-based surveillance study

•Largest GBS genome sequence sample of Chinese infants.•Baseline data for GBS surveillance and vaccine impact evaluation. Group B Streptococcus (GBS) is a leading cause of morbidity and mortality in young infants worldwide. This study aimed to investigate candidate GBS vaccine targets, virulence fac...

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Bibliographic Details

Published in:	Vaccine 2024-04, Vol.42 (16), p.3564
Main Authors:	Ji, Wenjing, Zhou, Haijian, Li, Jie, Britto, Carl D., Liu, Zheliang, Zhang, Wen, Du, Jiaxi, Madhi, Shabir A., Kwatra, Gaurav, Dangor, Ziyaad, Jin, Zhengjiang, Zhao, Hang, Zhao, Yifei, Fang, Yu, Li, Juan
Format:	Article
Language:	eng
Subjects:	Antibiotics Antimicrobial agents Antimicrobial resistance Bacteria Clindamycin Clinical trials Drug resistance Gene sequencing Genes Genomes Glycoproteins Group B Streptococcus Hospitals Infants Medical research Meningitis Morbidity Neonates Nucleotide sequence Phylogenetics Pili Population studies Proteins Resistance factors Resistance genes Review boards Sepsis Serotypes Streptococcus Streptococcus infections Surface protein Surveillance Vaccines Virulence Virulence factors Whole genome sequencing Womens health
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