Nanomaterials-based electrochemical biosensors for diagnosis of COVID-19

Since the outbreak of corona virus disease 2019 (COVID-19), this pandemic has caused severe death and infection worldwide. Owing to its strong infectivity, long incubation period, and nonspecific symptoms, the early diagnosis is essential to reduce risk of the severe illness. The electrochemical bio...

Full description

Saved in:
Bibliographic Details
Published in:Talanta (Oxford) 2024-07, Vol.274, p.125994, Article 125994
Main Authors: Liu, Xinxin, Sun, Yifan, Song, Huaiyu, Zhang, Wei, Liu, Tao, Chu, Zhenyu, Gu, Xiaoping, Ma, Zhengliang, Jin, Wanqin
Format: Article
Language:English
Subjects:
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
COVID-19
COVID-19 - diagnosis
COVID-19 - virology
COVID-19 Testing - instrumentation
COVID-19 Testing - methods
Detection principles
Electrochemical biosensors
Electrochemical Techniques - instrumentation
Electrochemical Techniques - methods
Humans
Nanomaterials
Nanostructures - chemistry
SARS-CoV-2 - isolation & purification
Synthesis design
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Since the outbreak of corona virus disease 2019 (COVID-19), this pandemic has caused severe death and infection worldwide. Owing to its strong infectivity, long incubation period, and nonspecific symptoms, the early diagnosis is essential to reduce risk of the severe illness. The electrochemical biosensor, as a fast and sensitive technique for quantitative analysis of body fluids, has been widely studied to diagnose different biomarkers caused at different infective stages of COVID-19 virus (SARS-CoV-2). Recently, many reports have proved that nanomaterials with special architectures and size effects can effectively promote the biosensing performance on the COVID-19 diagnosis, there are few comprehensive summary reports yet. Therefore, in this review, we will pay efforts on recent progress of advanced nanomaterials-facilitated electrochemical biosensors for the COVID-19 detections. The process of SARS-CoV-2 infection in humans will be briefly described, as well as summarizing the types of sensors that should be designed for different infection processes. Emphasis will be supplied to various functional nanomaterials which dominate the biosensing performance for comparison, expecting to provide a rational guidance on the material selection of biosensor construction for people. Finally, we will conclude the perspective on the design of superior nanomaterials-based biosensors facing the unknown virus in future. Due to its strong infectivity and long incubation period, COVID-19 has caused significant losses to people's health and socio-economic development. This article focuses on strategies for electrochemical detection of four types of biomarkers produced by SARS-CoV-2. Summarized the different advantages and applications of new nanomaterials in electrochemical biosensors, provided design prospects for new nanomaterial biosensors facing unknown viruses. [Display omitted] •The application of various regular structure nanomaterials in the detection of COVID-19 is summarized.•Construction of electrochemical sensors with different strategies based on the processes of SARS-CoV-2 into the human body.•Control of regular nanostructures is always a challenge for biosensing performance.•This review is of guidance to construct high-performance electrochemical biosensors for detection of infectious diseases.
ISSN:0039-9140
1873-3573
1873-3573
DOI:10.1016/j.talanta.2024.125994