Stimulation of Neural Cells by Lateral Currents in Conductive Layer-by-Layer Films of Single-Walled Carbon Nanotubes

The first example of neural stimulation through a SWNT material assembled by layer‐by‐layer deposition is described (see figure). Excitation by lateral currents in the nanotube coating results in the opening of voltage‐dependent Na+ ion channels. The experimental observations indicate the possibilit...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2006-11, Vol.18 (22), p.2975-2979
Main Authors: Gheith, M. K., Pappas, T. C., Liopo, A. V., Sinani, V. A., Shim, B. S., Motamedi, M., Wicksted, J. P., Kotov, N. A.
Format: Article
Language:English
Subjects:
Biocompatible materials
Biomedical applications
Carbon nanotubes
Carbon nanotubes, single‐walled
Layer-by-layer assembly
Nanocomposites
Neurons
single-walled
Thin films
Tissue engineering
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Summary:The first example of neural stimulation through a SWNT material assembled by layer‐by‐layer deposition is described (see figure). Excitation by lateral currents in the nanotube coating results in the opening of voltage‐dependent Na+ ion channels. The experimental observations indicate the possibility of engineering of implantable biomedical devices from SWNT/polymer multilayers to be used for neuron prosthesis, pain management, and muscle stimulation.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200600878