Infection risk and antimicrobial prophylaxis in bendamustine-treated patients with indolent non-Hodgkin lymphoma: An Australasian Lymphoma Alliance study

Infection and lymphopenia are established bendamustine-related complications. The relationship between lymphopenia severity and infection risk, and the role of antimicrobial prophylaxis, is not well described. This multicentre retrospective study analysed infection characteristics and antimicrobial...

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Bibliographic Details
Published in:British journal of haematology 2024-07, Vol.205 (1), p.146-157
Main Authors: Manos, Kate, Churilov, Leonid, Grigg, Andrew, Di Ciaccio, Pietro, Wong, Jonathan, Chandra Sekaran, Usha, Wight, Joel, Goh, Zhong, Jina, Hayden, Butler, Llewyn, Yannakou, Costas K, Hamad, Nada, Gregory, Gareth P, Gangatharan, Shane, Cochrane, Tara, Hawkes, Eliza A, Lasica, Masa
Format: Article
Language:English
Subjects:
Bacterial infections
CD20 antigen
Cytomegalovirus
Disease prevention
Herpes simplex
Hodgkin's lymphoma
Infections
Lymphocytes
Lymphoma
Lymphopenia
Nocardiosis
Prophylaxis
Varicella
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Summary:Infection and lymphopenia are established bendamustine-related complications. The relationship between lymphopenia severity and infection risk, and the role of antimicrobial prophylaxis, is not well described. This multicentre retrospective study analysed infection characteristics and antimicrobial prophylaxis in 302 bendamustine-treated indolent non-Hodgkin lymphoma patients. Lymphopenia (
ISSN:0007-1048
1365-2141
1365-2141
DOI:10.1111/bjh.19407