Exploratory analysis of glial fibrillary acidic protein and ubiquitin C-terminal hydrolase L1 in management of patients with mild neurological symptoms undergoing head computed tomography scan at the emergency department: a pilot study from a Croatian tertiary hospital

Diagnostic accuracy of glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1) in identification of intracranial abnormalities detected by computed tomography (CT) in mild traumatic brain injury (mTBI), and in patients with mild neurological symptoms not caused by head...

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Bibliographic Details
Published in:Laboratory medicine 2024-07, Vol.55 (4), p.492-497
Main Authors: Lapić, Ivana, Rogić, Dunja, Lončar Vrančić, Ana, Gornik, Ivan
Format: Article
Language:English
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Summary:Diagnostic accuracy of glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1) in identification of intracranial abnormalities detected by computed tomography (CT) in mild traumatic brain injury (mTBI), and in patients with mild neurological symptoms not caused by head trauma but suspected with a neurological disorder, was examined. GFAP and UCH-L1 were determined using the chemiluminescence immunoassays on the Alinity i analyzer (Abbott Laboratories). Significantly higher GFAP (median 53.8 vs 25.7 ng/L, P 
ISSN:0007-5027
1943-7730
1943-7730
DOI:10.1093/labmed/lmad116