The BALTO Registry: Long-term results of percutaneous BALloon pericardioTomy in oncological patients

The aim of this study was to analyze the efficacy and safety of percutaneous balloon pericardiotomy (PBP) in oncological patients who present with a malignant pericardial effusion (MPE). The use of PBP as a treatment for MPE is not standardized due to the limited evidence. Furthermore, the performan...

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Published in:Catheterization and cardiovascular interventions 2024-02, Vol.103 (3), p.482-489
Main Authors: Rivero-Santana, Borja, Jimenez-Valero, Santiago, Jurado-Roman, Alfonso, Galeote, Guillermo, Lopez-Fernandez, Teresa, Moreno, Raul
Format: Article
Language:English
Subjects:
Aged
Balloon Occlusion - adverse effects
Balloon treatment
Female
Humans
Male
Middle Aged
Patients
Pericardial Effusion - diagnostic imaging
Pericardial Effusion - etiology
Pericardial Effusion - therapy
Pericardiectomy - adverse effects
Pleural effusion
Prospective Studies
Treatment Outcome
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Summary:The aim of this study was to analyze the efficacy and safety of percutaneous balloon pericardiotomy (PBP) in oncological patients who present with a malignant pericardial effusion (MPE). The use of PBP as a treatment for MPE is not standardized due to the limited evidence. Furthermore, the performance of a second PBP for a recurrence after a first procedure is controversial. The BALTO Registry (BALloon pericardioTomy in Oncological patients) is a prospective, single-center, observational registry that includes consecutive PBP performed for MPE from October 2007 to February 2022. Clinical and procedural, characteristics, as well as clinical outcome were analyzed. Seventy-six PBP were performed in 61 patients (65% female). Mean age was of 66.4 ± 11.2 years. In 15 cases, a second PBP procedure was performed due to recurrence despite the first PBP. The procedure could be performed effectively in all cases with only two serious complications. Ninety-five percent of cases were discharged alive from the hospital. During a median follow-up of 6.3 months (interquartile range [IQR], 0.9-10.8), MPE recurred in 24.5% cases although no recurrences were reported after the second procedure. No evidence of malignant pleural effusion developed on follow-up. The median overall survival time was 5.8 months (IQR, 0.8-10.2) and the time to recurrence after the first PBP was 2.4 months (IQR, 0.7-4.5). PBP is a safe and effective treatment for MPE. It could be considered an acceptable therapy in most MPE, even in those who recur after a first procedure.
ISSN:1522-1946
1522-726X
DOI:10.1002/ccd.30953