Vitamin B12 insufficiency and deficiency: a review of nondisease risk factors

Vitamin B12 deficiency and insufficiency can lead to both hematological and neurological impairments. This review examines nondisease causes and risk factors associated with dietary availability, such as eating habits, food processing, cooking techniques, and bioavailability, as well as increased ph...

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Bibliographic Details
Published in:Scandinavian journal of clinical and laboratory investigation 2023-12, Vol.83 (8), p.533-539
Main Authors: Abuyaman, Omar, Abdelfattah, Ali, Shehadeh-Tout, Faten, Deeb, Ahmad A, Hatmal, Ma'mon M
Format: Article
Language:English
Subjects:
Aged
Diet, Vegetarian - adverse effects
Humans
Infant
Infant, Newborn
Infant, Premature
Risk Factors
Vitamin B 12
Vitamin B 12 Deficiency - drug therapy
Vitamin B 12 Deficiency - etiology
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Summary:Vitamin B12 deficiency and insufficiency can lead to both hematological and neurological impairments. This review examines nondisease causes and risk factors associated with dietary availability, such as eating habits, food processing, cooking techniques, and bioavailability, as well as increased physiological needs and iatrogenic factors linked to medication use or surgical procedures. As a result of these nondisease influences, groups at higher risk include vegans, vegetarians, older adults, individuals with limited diets, breastfed and preterm infants, and those who primarily consume foods prepared or cooked in ways that reduce vitamin B12 content, as well as individuals on certain medications or who have undergone specific surgeries. Recognizing these diverse risk factors helps develop strategies for prevention and intervention to minimize the adverse health effects related to B12 deficiency and insufficiency.
ISSN:0036-5513
1502-7686
DOI:10.1080/00365513.2023.2297357